Diversity of Agaricomycetes in southern South America and their bioactive natural products

被引:6
作者
Gomez-Espinoza, Jonhatan [1 ]
Riquelme, Cristian [2 ,3 ]
Romero-Villegas, Enzo [1 ]
Ahumada-Rudolph, Ramon [1 ]
Novoa, Vanessa [4 ]
Mendez, Paola [1 ]
Millar, Camila [1 ]
Fernandez-Alarcon, Naomi [1 ]
Garnica, Sigisfredo [3 ]
Rajchenberg, Mario [5 ,6 ]
Cabrera-Pardo, Jaime R. [1 ]
机构
[1] Univ Bio Bio, Lab Quim Aplicada & Sustentable LabQAS, Dept Quim, Ave Collao 1202, Concepcion 4030000, Chile
[2] Univ Austral Chile, Escuela Grad, Fac Ciencias, Programa Doctorado Ciencias Menc Ecol & Evoluc, Valdivia, Chile
[3] Univ Austral Chile, Lab Micol, Inst Bioquim & Microbiol, Valdivia, Chile
[4] Univ Tarapaca, Inst Alta Invest, Arica, Chile
[5] Ctr Invest & Extens Forestal Andino Patagon CIEFA, Chubut, Argentina
[6] Consejo Nacl Invest Cient & Tecn CONICET, Buenos Aires, Argentina
关键词
Andean region; bioactivity; chemodiversity; fungi; secondary metabolites; EDIBLE MUSHROOM; GRIFOLA-GARGAL; SECONDARY METABOLITES; ANTIOXIDANT PROPERTIES; BIOLOGICAL-ACTIVITY; FUNGI; BASIDIOMYCOTA; FERMENTATIONS; AGARICALES; MYCOFLORA;
D O I
10.1080/14786419.2023.2244126
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Fungi have a unique metabolic plasticity allowing them to produce a wide range of natural products. Since the discovery of penicillin, an antibiotic of fungal origin, substantial efforts have been devoted globally to search for fungal-derived natural bioactive products. Andean region forests represent one of the few undisturbed ecosystems in the world with little human intervention. While these forests display a rich biological diversity, mycological and chemical studies in these environments have been scarce. This review aims to summarise all the efforts regarding the chemical or bioactivity analyses of Agaricomycetes (Basidiomycota) from southern South America environments. Overall, herein we report a total of 147 fungal species, 21 of them showing chemical characterisation and/or biological activity. In terms of chemical cores, furans, chlorinated phenol derivatives, polyenes, lactones, terpenes and himanimides have been reported. These natural products displayed a range of biological activities including antioxidant, antimicrobial, antifungal, neuroprotective and osteoclast-forming suppressing effects.
引用
收藏
页码:3389 / 3403
页数:15
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