Green Synthesis of Gold Nanoparticles Using Pithecellobium dulce Leaf Extract and Its Biological Activities

被引:2
作者
Vincent, Jacob [1 ]
Lekha, N. Chandra [1 ]
机构
[1] Kamaraj Coll, Dept Chem, Thoothukudi 628003, Tamil Nadu, India
关键词
Antibacterial activity; Anticancer activity; Gold nanoparticles; Pithecellobium dulce leaf extract; SILVER; BIOSYNTHESIS;
D O I
10.1002/ceat.202100618
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Pithecellobium dulce leaf extract was used to synthesize gold nanoparticles (AuNPs) for the first time. This bio-synthesized novel material was investigated by UV-visible spectra, high-resolution transmission electron microscopy, powder diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive analysis by X-ray. Excellent antibacterial activity was revealed against Staphylococcus aureus and Escherichia coli. Significant antifungal activities by the AuNPs were also demonstrated. The analysis of AuNPs by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay proved 100 % toxic effect and the minimum value of half-maximal inhibitory concentration (IC50) indicates that it is safe to be used as drug in the medical field.
引用
收藏
页码:1424 / 1431
页数:8
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