Applications of Stimuli-Responsive Hydrogels in Bone and Cartilage Regeneration

被引：20
|
作者：
Ni, Xiaoqi
Xing, Xin
Deng, Yunfan
Li, Zhi [1 ]
机构：
[1] Wuhan Univ, Sch & Hosp Stomatol, State Key Lab Breeding Base Basic Sci Stomatol Hub, Minist Educ, Wuhan 430079, Peoples R China
来源：
PHARMACEUTICS | 2023年 / 15卷 / 03期
关键词：
stimuli-responsive; hydrogels; bone; cartilage; regeneration; MAGNETIC NANOCOMPOSITE HYDROGEL; MESENCHYMAL STEM-CELLS; DRUG-DELIVERY; OSTEOGENIC DIFFERENTIATION; THERMOSENSITIVE HYDROGELS; INTELLIGENT MATERIALS; INJECTABLE HYDROGELS; CATHEPSIN-K; TISSUE; GROWTH;
D O I：
10.3390/pharmaceutics15030982
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Bone and cartilage regeneration is an area of tremendous interest and need in health care. Tissue engineering is a potential strategy for repairing and regenerating bone and cartilage defects. Hydrogels are among the most attractive biomaterials in bone and cartilage tissue engineering, mainly due to their moderate biocompatibility, hydrophilicity, and 3D network structure. Stimuli-responsive hydrogels have been a hot topic in recent decades. They can respond to external or internal stimulation and are used in the controlled delivery of drugs and tissue engineering. This review summarizes current progress in the use of stimuli-responsive hydrogels in bone and cartilage regeneration. The challenges, disadvantages, and future applications of stimuli-responsive hydrogels are briefly described.
引用
收藏
页数：25
相关论文
共 50 条
  • [31] Electrospun Nanofibrous Materials as Stimuli-Responsive Polymerized Hydrogels
    Jahan, Kazi I.
    Goponenko, Alexander
    Dzenis, Yuris
    MACROMOLECULAR SYMPOSIA, 2016, 365 (01) : 118 - 127
  • [32] Designing Composite Stimuli-Responsive Hydrogels for Wound Healing Applications: The State-of-the-Art and Recent Discoveries
    Michalicha, Anna
    Belcarz, Anna
    Giannakoudakis, Dimitrios A.
    Staniszewska, Magdalena
    Barczak, Mariusz
    MATERIALS, 2024, 17 (02)
  • [33] Ultrasound-Induced Drug Release from Stimuli-Responsive Hydrogels
    Yeingst, Tyus J.
    Arrizabalaga, Julien H.
    Hayes, Daniel J.
    GELS, 2022, 8 (09)
  • [34] Recent Advances of Stimuli-Responsive Polysaccharide Hydrogels in Delivery Systems: A Review
    Zhang, Yunzhen
    Dong, Lezhen
    Liu, Lingyi
    Wu, Zufang
    Pan, Daodong
    Liu, Lianliang
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 70 (21) : 6300 - 6316
  • [35] Designing polymers with stimuli-responsive degradation for biomedical applications
    Li, Chuanfeng
    Deng, Zhengyu
    Gillies, Elizabeth R.
    CURRENT OPINION IN BIOMEDICAL ENGINEERING, 2023, 25
  • [36] Stimuli-Responsive Polysaccharide-Based Smart Hydrogels and Their Emerging Applications
    Srivastava, Nandita
    Choudhury, Anirban Roy
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2023, 62 (02) : 841 - 866
  • [37] Stimuli-responsive supramolecules for bone tissue engineering
    Sharma, Akanksha
    Sharma, Pramod Kumar
    Malviya, Rishabha
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2020, 10 (02): : 5122 - 5127
  • [38] Application Properties of Stimuli-Responsive Polyglycerol Hydrogels
    Salehpour, Somaieh
    Dube, Marc A.
    JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2012, 49 (02): : 103 - 110
  • [39] Numerical modeling of heterogeneous stimuli-responsive hydrogels
    Rahmat, Amin
    Altunkeyik, Berk
    Shadloo, Mostafa Safdari
    Montenegro-Johnson, Tom
    PHYSICAL REVIEW E, 2024, 110 (05)
  • [40] Stimuli-responsive hydrogels for intratumoral drug delivery
    Marques, Ana C.
    Costa, Paulo J.
    Velho, Sergia
    Amaral, Maria H.
    DRUG DISCOVERY TODAY, 2021, 26 (10) : 2397 - 2405
12345