link-ancestors: fast simulation of local ancestry with tree sequence software

被引：4
作者：
Tsambos, Georgia [1 ,2 ,3 ]
Kelleher, Jerome [4 ]
Ralph, Peter [5 ]
Leslie, Stephen [1 ,2 ,6 ]
Vukcevic, Damjan [1 ,2 ,7 ]
机构：
[1] Univ Melbourne, Sch Math & Stat, Melbourne, Vic 3052, Australia
[2] Univ Melbourne, Melbourne Integrat Genom, Melbourne, Vic 3052, Australia
[3] Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA
[4] Univ Oxford, Big Data Inst, Oxford OX3 7LF, England
[5] Univ Oregon, Inst Ecol & Evolut, Eugene, OR 97403 USA
[6] Univ Melbourne, Sch BioSci, Melbourne, Vic 3052, Australia
[7] Monash Univ, Dept Econometr & Business Stat, Melbourne, Vic 3168, Australia
来源：
BIOINFORMATICS ADVANCES | 2023年 / 3卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1093/bioadv/vbad163
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
It is challenging to simulate realistic tracts of genetic ancestry on a scale suitable for simulation-based inference. We present an algorithm that enables this information to be extracted efficiently from tree sequences produced by simulations run with msprime and SLiM.
引用
收藏
页数：4
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