Effect of Simultaneous Intake of MediumChain Triglyceride and d-Allulose on Body Fat Accumulation in Rats Fed a High-Fat Diet

被引：1

作者：

Matsuo, Tatsuhiro ^{[1
]}

Yokoyama, Chihiro ^{[1
]}

Yamada, Takako ^{[2
]}

Iida, Tetsuo ^{[2
]}

Mochizuki, Susumu ^{[1
]}

Yoshihara, Akihide ^{[1
]}

Akimitsu, Kazuya ^{[1
]}

机构：

[1] Kagawa Univ, Fac Agr, 2393 Ikenobe, Miki, Kagawa 7610795, Japan

[2] Matsutani Chem Ind Co Ltd, Res & Dev, 5-3 Kita Itami, Itami, Hyogo 6648508, Japan

来源：

CURRENT TOPICS IN NUTRACEUTICAL RESEARCH | 2023年 / 21卷 / 03期

关键词：

Body fat; D-allulose; Medium-chain triglyceride; Rat; MEDIUM-CHAIN TRIGLYCERIDES; D-PSICOSE; ENERGY-EXPENDITURE; D-FRUCTOSE; DOUBLE-BLIND; METABOLISM; METAANALYSIS; LIPOGENESIS; ENZYMES; OBESITY;

D O I：

10.37290/ctnr2641-452X.21:242-247

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Medium-chain triglycerides, lipids containing three 6-12 carbon medium-chain fatty acids, have antiobesity effects because they do not promote lipogenesis. D-Allulose, a low-calorie epimer of fructose commercially used as a low-calorie sweetener, suppresses hepatic lipogenesis and enhances postprandial fat oxidation. Therefore, we have explored whether a simultaneous intake of medium-chain fatty acids and D-Allulose may exhibit a greater reduction in de novo lipogenesis and increase their antiobesity effects. To this end, 32 male Wistar rats were divided into four treatment groups of equal sizes: control, 3% D-Allulose-treated, 5% medium-chain triglycerides-treated, and 3% D-Allulose + 5% medium-chain triglycerides-treated. After 8 weeks of ad libitum exposure to these diets, D-Allulose significantly decreased intra-abdominal adipose tissue and total body fat weight, with or without medium-chain triglyceride supplementation. The antiobesity effect of D-Allulose was observed with or without dietary medium-chain triglyceride supplementation in high-fat diet-induced obese rats, but no synergistic effect was detected between D-Allulose and medium-chain triglycerides.

引用

页码：242 / 247

页数：6

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