A pre-TCRα-independent pathway of αβ T cell differentiation

被引：0

作者：

Minton, Kirsty

机构：

[1] Nature Reviews Immunology,

来源：

NATURE REVIEWS IMMUNOLOGY | 2024年 / 24卷 / 05期

关键词：

D O I：

10.1038/s41577-024-01024-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A study in Science reports 10 individuals with pre-TCR alpha deficiency who have late-onset or no clinical phenotype, which suggests that alpha beta T cells can develop through a pre-TCR alpha-independent, non-canonical rescue pathway.

引用

页码：305 / 305

页数：1

共 50 条

[21] Opposite ability of pre-TCR and αβTCR to induce apoptosis [J].

Steff, AM ;

Trop, S ;

Maira, M ;

Drouin, J ;

Hugo, P .

JOURNAL OF IMMUNOLOGY, 2001, 166 (08) :5044-5050

[22] New components assembled with TCR or pre-TCR complex [J].

Yamazaki, T ;

Hamano, Y ;

Takase, K ;

Mann, M ;

Saito, T .

10TH INTERNATIONAL CONGRESS ON IMMUNOLOGY, VOLS 1 AND 2, 1998, :189-194

[23] Notch3 and pre-TCR interaction differentially regulate T cell development and leukemogenesis [J].

Bellavia, D. ;

Campese, A. F. ;

Talora, C. ;

Checquolo, S. ;

Vacca, A. ;

Felli, M. P. ;

Gulino, A. ;

Screpanti, I. .

IMMUNOLOGY, 2007, 120 :33-33

[24] Obligatory role for cooperative signaling by pre-TCR and notch during thymocyte differentiation [J].

Ciofani, M ;

Schmitt, TM ;

Ciofani, A ;

Michie, AM ;

Çuburu, N ;

Aublin, A ;

Maryanski, JL ;

Zúñiga-Pflücker, JC .

JOURNAL OF IMMUNOLOGY, 2004, 172 (09) :5230-5239

[25] Constitutive expression of the pre-TCR enables development of mature T cells [J].

Schnell, Silke ;

Demolliere, Corinne ;

van den Berk, Paul ;

Kirberg, Joerg ;

Jacobs, Heinz .

INTERNATIONAL IMMUNOLOGY, 2006, 18 (06) :911-920

[26] NMR-directed design of pre-TCRβ and pMHC molecules implies a distinct geometry for pre-TCR relative to αβTCR recognition of pMHC [J].

Mallis, Robert J. ;

Arthanari, Haribabu ;

Lang, Matthew J. ;

Reinherz, Ellis L. ;

Wagner, Gerhard .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (03) :754-766

[27] A clonotype-independent pre-TCR complex and its downstream signals can support transformation of thymic T cells [J].

Hathcock, Karen S. ;

An, Joseph B. H. ;

Hodes, Richard J. .

JOURNAL OF IMMUNOLOGY, 2018, 200 (01)

[28] RhoH modulates pre-TCR and TCR signalling by regulating LCK [J].

Wang, Hong ;

Zeng, Xin ;

Fan, Zhigang ;

Lim, Bing .

CELLULAR SIGNALLING, 2011, 23 (01) :249-258

[29] Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros [J].

Winandy, S ;

Wu, L ;

Wang, JH ;

Georgopoulos, K .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (08) :1039-1048

[30] E2A and HEB activate the pre-TCRα promoter during immature T cell development [J].

Takeuchi, A ;

Yamasaki, S ;

Takase, K ;

Nakatsu, F ;

Arase, H ;

Onodera, M ;

Saito, T .

JOURNAL OF IMMUNOLOGY, 2001, 167 (04) :2157-2163

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