Improving the Outcome of Patients With Heart Failure: Assessment of Iron Deficiency and Intravenous Iron Replacement

被引:2
作者
Yera, Hassan O. [1 ]
Khan, Ahsan [2 ]
Akinlade, Olawale M. [3 ]
Champsi, Asgher [2 ]
Glouzon, Van Nam J. [4 ]
Spencer, Charles [2 ]
机构
[1] Shrewsbury & Telford Hosp NHS Trust, Internal Med, Telford, England
[2] New Cross Hosp, Cardiol Heart & Lung Ctr, Wolverhampton, England
[3] Dumfries & Galloway Royal Infirm, Cardiol, Dumfries, Scotland
[4] New Cross Hosp, Internal Med Heart & Lung Ctr, Wolverhampton, England
关键词
morbidity and mortality; heart failure with reduced ejection fraction; quality improvement; ferric carboxymaltose; iron deficiency anaemia; REDUCED EJECTION FRACTION; FERRIC CARBOXYMALTOSE; EXERCISE CAPACITY; ANEMIA; SUBANALYSIS; PREVALENCE; THERAPY;
D O I
10.7759/cureus.47027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Iron deficiency (ID) has been shown to be a significant co-morbidity in patients with heart failure (HF), independent of their anaemia status. Correction of ID has been shown to improve quality of life, recurrent heart failure hospitalizations and morbidity. A quality improvement project was designed to improve the assessment and treatment of iron deficiency in HF patients in our tertiary care centre.Methods and results An initial baseline dataset was collected, followed by two cycles of interventions to help improve the care of HF patients admitted to our hospital over a two-month period. The Plan-Do-Study-Act (PDSA) cycle approach was applied, with the first intervention involving raising awareness of the importance and need to assess the iron status of HF patients through education provided to doctors, nurses and patients. Furthermore, information leaflets were produced and disseminated across the medical wards and through social media forums. The post-intervention datasets were collected and compared to the baseline outcomes. Baseline data showed that only four (20%) of heart failure patients had their iron status checked. Following the interventions, screening for ID increased to 80% (16), of which 85% (11) of those who identified as iron deficient received intravenous iron replacement.Conclusion The project was successful in improving the practice of screening for iron deficiency and intravenous replacement of iron in patients with HF.
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相关论文
共 19 条
[1]   Anemia and Iron Deficiency in Heart Failure: Current Concepts and Emerging Therapies [J].
Anand, Inder S. ;
Gupta, Pankaj .
CIRCULATION, 2018, 138 (01) :80-98
[2]   Effects of ferric carboxymaltose on hospitalisations and mortality rates in iron-deficient heart failure patients: an individual patient data meta-analysis [J].
Anker, Stefan D. ;
Kirwan, Bridget-Anne ;
van Veldhuisen, Dirk J. ;
Filippatos, Gerasimos ;
Comin-Colet, Josep ;
Ruschitzka, Frank ;
Luscher, Thomas F. ;
Arutyunov, Gregory P. ;
Motro, Michael ;
Mori, Claudio ;
Roubert, Bernard ;
Pocock, Stuart J. ;
Ponikowski, Piotr .
EUROPEAN JOURNAL OF HEART FAILURE, 2018, 20 (01) :125-133
[3]   Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency. [J].
Anker, Stefan D. ;
Comin Colet, Josep ;
Filippatos, Gerasimos ;
Willenheimer, Ronnie ;
Dickstein, Kenneth ;
Drexler, Helmut ;
Luescher, Thomas F. ;
Bart, Boris ;
Banasiak, Waldemar ;
Niegowska, Joanna ;
Kirwan, Bridget-Anne ;
Mori, Claudio ;
Rothe, Barbara von Eisenhart ;
Pocock, Stuart J. ;
Poole-Wilson, Philip A. ;
Ponikowski, Piotr .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (25) :2436-2448
[4]   Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management [J].
Cappellini, Maria Domenica ;
Comin-Colet, Josep ;
de Francisco, Angel ;
Dignass, Axel ;
Doehner, Wolfram ;
Lam, Carolyn S. P. ;
Macdougall, Iain C. ;
Rogler, Gerhard ;
Camaschella, Clara ;
Kadir, Rezan ;
Kassebaum, Nicholas J. ;
Spahn, Donat R. ;
Taher, Ali T. ;
Musallam, Khaled M. .
AMERICAN JOURNAL OF HEMATOLOGY, 2017, 92 (10) :1068-1078
[5]   The effect of intravenous ferric carboxymaltose on health-related quality of life in patients with chronic heart failure and iron deficiency: a subanalysis of the FAIR-HF study [J].
Comin-Colet, Josep ;
Lainscak, Mitja ;
Dickstein, Kenneth ;
Filippatos, Gerasimos S. ;
Johnson, Patrick ;
Luescher, Thomas F. ;
Mori, Claudio ;
Willenheimer, Ronnie ;
Ponikowski, Piotr ;
Anker, Stefan D. .
EUROPEAN HEART JOURNAL, 2013, 34 (01) :30-38
[6]   Intravenous ferric carboxymaltose in iron-deficient chronic heart failure patients with and without anaemia: a subanalysis of the FAIR-HF trial [J].
Filippatos, Gerasimos ;
Farmakis, Dimitrios ;
Colet, Josep Comin ;
Dickstein, Kenneth ;
Luescher, Thomas F. ;
Willenheimer, Ronnie ;
Parissis, John ;
Gaudesius, Giedrius ;
Mori, Claudio ;
Rothe, Barbara von Eisenhart ;
Greenlaw, Nicola ;
Ford, Ian ;
Ponikowski, Piotr ;
Anker, Stefan D. .
EUROPEAN JOURNAL OF HEART FAILURE, 2013, 15 (11) :1267-1276
[7]  
Iorio A, 2018, EUR J HEART FAIL, V20, P1257, DOI 10.1002/ejhf.1202
[8]   Effects of intravenous iron therapy in iron-deficient patients with systolic heart failure: a meta-analysis of randomized controlled trials [J].
Jankowska, Ewa A. ;
Tkaczyszyn, Michal ;
Suchocki, Tomasz ;
Drozd, Marcin ;
von Haehling, Stephan ;
Doehner, Wolfram ;
Banasiak, Waldemar ;
Filippatos, Gerasimos ;
Anker, Stefan D. ;
Ponikowski, Piotr .
EUROPEAN JOURNAL OF HEART FAILURE, 2016, 18 (07) :786-795
[9]   Iron deficiency: an ominous sign in patients with systolic chronic heart failure [J].
Jankowska, Ewa A. ;
Rozentryt, Piotr ;
Witkowska, Agnieszka ;
Nowak, Jolanta ;
Hartmann, Oliver ;
Ponikowska, Beata ;
Borodulin-Nadzieja, Ludmila ;
Banasiak, Waldemar ;
Polonski, Lech ;
Filippatos, Gerasimos ;
McMurray, John J. V. ;
Anker, Stefan D. ;
Ponikowski, Piotr .
EUROPEAN HEART JOURNAL, 2010, 31 (15) :1872-1880
[10]   Iron deficiency in chronic heart failure: An international pooled analysis [J].
Klip, IJsbrand T. ;
Comin-Colet, Josep ;
Voors, Adriaan A. ;
Ponikowski, Piotr ;
Enjuanes, Cristina ;
Banasiak, Waldemar ;
Lok, Dirk J. ;
Rosentryt, Piotr ;
Torrens, Ainhoa ;
Polonski, Lech ;
van Veldhuisen, Dirk J. ;
van der Meer, Peter ;
Jankowska, Ewa A. .
AMERICAN HEART JOURNAL, 2013, 165 (04) :575-+