Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report

被引：2

作者：

Mobayed, Hassan ^{[1
]}

Al-Nesf, Maryam Ali ^{[1
]}

Robles-Velasco, Karla ^{[2
,3
]}

Cherrez-Ojeda, Ivan ^{[2
,3
]}

Ensina, Luis Felipe ^{[4
]}

Maurer, Marcus ^{[5
,6
,7
,8
]}

机构：

[1] Hamad Med Corp, Allergy & Immunol Div, Dept Med, Doha, Qatar

[2] Respiralab Res Grp, Guayaquil, Ecuador

[3] Univ Espiritu Santo, Samborondon, Ecuador

[4] Univ Fed Sao Paulo, Dept Pediat, Div Allergy Immunol Rheumatol, Sao Paulo, Brazil

[5] Charite, Inst Allergol, GA2LEN Urticaria Ctr Reference & Excellence UACRE, Berlin, Germany

[6] Free Univ Berlin, Berlin, Germany

[7] Humboldt Univ, Berlin, Germany

[8] Fraunhofer Inst Translat Med & Pharmacol ITMP, Allergol & Immunol, Berlin, Germany

来源：

FRONTIERS IN ALLERGY | 2023年 / 4卷

关键词：

anaphylaxis; exercise-induced anaphylaxis; omalizumab; diagnosis and management; co-factors;

D O I：

10.3389/falgy.2023.1228495

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Exercise-induced anaphylaxis (EIA) is a rare disorder in which anaphylaxis occurs exclusively after physical activity. Here, we report a case of severe EIA where anaphylaxis was initially only induced by strenuous exercise. Suddenly the anaphylaxis got out of control to the degree that usual daily activities triggered it. Exposure to a hot and humid environment appeared to be a cofactor for the development of severe symptoms resistant to usual preventive measures. Treatment with omalizumab (anti-IgE) was initiated and resulted in marked improvement. We discuss unique aspects of this case in comparison to published information on the clinical features, triggering cofactors, diagnosis, and treatment of EIA.

引用

页数：6

共 23 条

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