Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"

被引：4

作者：

Karimy, Jason K. ^{[1
]}

Newville, Jessie C. ^{[2
]}

Sadegh, Cameron ^{[3
,4
,11
]}

Morris, Jill A. ^{[5
]}

Monuki, Edwin S. ^{[6
,7
]}

Limbrick, David D. ^{[8
,9
]}

McAllister II, James P. ^{[8
,9
]}

Koschnitzky, Jenna E. ^{[10
]}

Lehtinen, Maria K. ^{[11
]}

Jantzie, Lauren L. ^{[2
,12
]}

机构：

[1] Mt Area Hlth Educ Ctr Boone, Dept Family Med, Boone, NC 28607 USA

[2] Johns Hopkins Sch Med, Johns Hopkins Childrens Ctr, Dept Pediat & Neurosurg, Baltimore, MD 21287 USA

[3] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA 02114 USA

[4] Harvard Med Sch, Boston, MA 02114 USA

[5] Natl Inst Neurol Disorders & Stroke, Neurosci Ctr, NIH, 6001 Execut Blvd,NSC Rm 2112, Bethesda, MD 20892 USA

[6] Univ Calif Irvine, Dept Pathol & Lab Med, Irvine, CA 92697 USA

[7] Univ Calif Irvine, Dept Dev & Cell Biol, Irvine, CA 92697 USA

[8] Washington Univ, Dept Neurosurg, Sch Med St Louis, St Louis, MO 63110 USA

[9] Washington Univ, Dept Pediat, Sch Med St Louis, St Louis, MO 63110 USA

[10] Hydrocephalus Assoc, Bethesda, MD 20814 USA

[11] Boston Childrens Hosp, Dept Pathol, Boston, MA 02115 USA

[12] Kennedy Krieger Inst, Baltimore, MD 21287 USA

来源：

FLUIDS AND BARRIERS OF THE CNS | 2023年 / 20卷 / 01期

关键词：

Hydrocephalus; Posthemorrhagic; Post-infectious; Intraventricular hemorrhage; Germinal matrix hemorrhage; Cilia; Ependyma; Cerebrospinal fluid; ENDOSCOPIC 3RD VENTRICULOSTOMY; MULTICILIATED EPENDYMAL CELLS; PLEXUS EPITHELIAL-CELLS; NEURAL STEM-CELLS; CHOROID-PLEXUS; CEREBROSPINAL-FLUID; PRETERM INFANTS; INTRAVENTRICULAR HEMORRHAGE; LYSOPHOSPHATIDIC ACID; CILIARY MOTILITY;

D O I：

10.1186/s12987-023-00406-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia).

引用

页数：17

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