Paraganglioma at the cerebellopontine angle: A case report and review of literature

被引:0
作者
Akhtar, Nadeem [1 ]
Shahid, Fatimah [2 ]
Ali, Alishba Shezal [2 ]
Muhammad, Qurat Ul Ain [2 ]
Azam, Noor Mahal [2 ]
Dhakal, Bishal [3 ,5 ]
Ibrahim, Muhammad [2 ]
Nadeem, Nehal [4 ]
机构
[1] Rawalpindi Teaching Hosp, Dept Neurosurg, Punjab, Pakistan
[2] Rawalpindi Med Univ, Dept Neurosurg, Punjab, Pakistan
[3] Nepalese Army Inst Hlth Sci, Dept Neurol, Kathmandu, Nepal
[4] Shifa Coll Med, Dept Internal Med, Islamabad, Pakistan
[5] Nepalese Army Inst Hlth & Sci, Kathmandu 44600, Nepal
关键词
catecholamine secreting tumor; cerebellopontine angle; extra-adrenal paraganglioma; head and neck neoplasms; hypertension; hypoxia-inducible factor (HIF)-1 alpha; HEAD; NECK;
D O I
10.1002/ccr3.8584
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Paragangliomas (PGLs) are rare neuroendocrine tumors. Sometimes, these tumors secrete excessive catecholamines, which results in the manifestations of various signs and symptoms, usually with a triad of hypertension, tachycardia, and headache. We report the case of a 42-year-old woman presenting with uncontrolled hypertension, right facial palsy, vomiting, and disturbed gait. Diagnosis for PGL was confirmed on postoperative histological examination of the excised mass and correlated with preoperative clinical and radiological findings. Tumor excision was done via a suboccipital craniotomy approach. Our case presents the typically severe features of a jugulotympanic PGL, but most importantly, it highlights the necessity of biochemical diagnosing, thorough probing of the causes of hypertension, and a multi-disciplinary approach in dealing with these tumors. Moreover, the case emphasizes necessitating the use of preoperative embolization in vascular tumors of the head and neck to avoid a hemorrhagic crisis during surgery. Unfortunately, due to a lack of adequate hospital funds, the surgeon had to proceed without preoperative embolization. Despite such a risk, the excision was a success.
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页数:6
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