Gel implant heals muscles with electrical stimulation

被引：1

作者：

Radisic, Milica ^{[1
,2
]}

机构：

[1] Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada

[2] Univ Toronto, Dept Chem Engn & Appl Chem, Toronto, ON, Canada

来源：

NATURE | 2023年 / 623卷 / 7985期

关键词：

HYDROGELS;

D O I：

10.1038/d41586-023-03211-2

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An electrically conductive hydrogel injected into an injured muscle can help the muscle to regenerate and reconnect with the nervous system. This effective soft prosthesis has enabled rats to walk soon after muscular injury.

引用

页码：37 / 38

页数：2

共 10 条

[1] 3D Bioelectronics with a Remodellable Matrix for Long-Term Tissue Integration and Recording [J].

Boys, Alexander J. ;

Carnicer-Lombarte, Alejandro ;

Gueemes-Gonzalez, Amparo ;

van Niekerk, Douglas C. ;

Hilton, Sam ;

Barone, Damiano G. ;

Proctor, Christopher M. ;

Owens, Roisin M. ;

Malliaras, George G. .

ADVANCED MATERIALS, 2023, 35 (08)

[2] Hyaluronic Acid Hydrogels for Biomedical Applications [J].

Burdick, Jason A. ;

Prestwich, Glenn D. .

ADVANCED MATERIALS, 2011, 23 (12) :H41-H56

[3] Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration [J].

Choi, Yeon Sik ;

Hsueh, Yuan-Yu ;

Koo, Jahyun ;

Yang, Quansan ;

Avila, Raudel ;

Hu, Buwei ;

Xie, Zhaoqian ;

Lee, Geumbee ;

Ning, Zheng ;

Liu, Claire ;

Xu, Yameng ;

Lee, Young Joong ;

Zhao, Weikang ;

Fang, Jun ;

Deng, Yujun ;

Lee, Seung Min ;

Vazquez-Guardado, Abraham ;

Stepien, Iwona ;

Yan, Ying ;

Song, Joseph W. ;

Haney, Chad ;

Oh, Yong Suk ;

Liu, Wentai ;

Yun, Hong-Joon ;

Banks, Anthony ;

MacEwan, Matthew R. ;

Ameer, Guillermo A. ;

Ray, Wilson Z. ;

Huang, Yonggang ;

Xie, Tao ;

Franz, Colin K. ;

Li, Song ;

Rogers, John A. .

NATURE COMMUNICATIONS, 2020, 11 (01)

[4]

DAHL LB, 1989, J DEV PHYSIOL, V12, P209

[5] Electrical bioadhesive interface for bioelectronics [J].

Deng, Jue ;

Yuk, Hyunwoo ;

Wu, Jingjing ;

Varela, Claudia E. ;

Chen, Xiaoyu ;

Roche, Ellen T. ;

Guo, Chuan Fei ;

Zhao, Xuanhe .

NATURE MATERIALS, 2021, 20 (02) :229-+

[6] Boronic acid-containing hydrogels: synthesis and their applications [J].

Guan, Ying ;

Zhang, Yongjun .

CHEMICAL SOCIETY REVIEWS, 2013, 42 (20) :8106-8121

[7] Recent advances in hyaluronic acid hydrogels for biomedical applications [J].

Highley, Christopher B. ;

Prestwich, Glenn D. ;

Burdick, Jason A. .

CURRENT OPINION IN BIOTECHNOLOGY, 2016, 40 :35-40

[8] Injectable tissue prosthesis for instantaneous closed-loop rehabilitation [J].

Jin, Subin ;

Choi, Heewon ;

Seong, Duhwan ;

You, Chang-Lim ;

Kang, Jong-Sun ;

Rho, Seunghyok ;

Lee, Won Bo ;

Son, Donghee ;

Shin, Mikyung .

NATURE, 2023, 623 (7985) :58-+

[9] Adaptive self-healing electronic epineurium for chronic bidirectional neural interfaces [J].

Song, Kang-Il ;

Seo, Hyunseon ;

Seong, Duhwan ;

Kim, Seunghoe ;

Yu, Ki Jun ;

Kim, Yu-Chan ;

Kim, Jinseok ;

Kwon, Seok Joon ;

Han, Hyung-Seop ;

Youn, Inchan ;

Lee, Hyojin ;

Son, Donghee .

NATURE COMMUNICATIONS, 2020, 11 (01)

[10] Adaptive conductive electrotherapeutic scaffolds for enhanced peripheral nerve regeneration and stimulation [J].

Srinivasan, Shriya S. ;

Gfrerer, Lisa ;

Karandikar, Paramesh ;

Som, Avik ;

Alshareef, Amro ;

Liu, Sabrina ;

Higginbotham, Haley ;

Ishida, Keiko ;

Hayward, Alison ;

Kalva, Sanjeeva P. ;

Langer, Robert ;

Traverso, Giovanni .

MED, 2023, 4 (08) :541-+

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