Delivery of BDNF through a Pluripotent Stem Cell-Based Platform Ameliorates Behavioral Deficits in a Mouse Model of Huntington's Disease

被引:0
作者
Selvaraj, Sridhar [1 ]
Simmons, Danielle A. [2 ]
Chen, Tingshuo [2 ]
Cao, Gloria Y. [2 ]
Camelo, Talita S. [2 ]
McHugh, Tyne L. M. [2 ]
Gonzalez, Selena [2 ]
Martin, Renata M. [1 ]
Simanauskaite, Juste M. [2 ]
Uchida, Nobuko [3 ]
Longo, Frank M. [2 ]
Porteus, Matthew H. [1 ]
机构
[1] Stanford Univ, Sch Med, Pediat, Stanford, CA USA
[2] Stanford Univ, Sch Med, Neurol & Neurol Sci, Stanford, CA USA
[3] BOCO Silicon Valley, ReGen Med Div, Palo Alto, CA USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
33
引用
收藏
页码:18 / 18
页数:1
相关论文
共 50 条
  • [1] Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery
    Zuccato, C
    Liber, D
    Ramos, C
    Tarditi, A
    Rigamonti, D
    Tartari, M
    Valenza, M
    Cattaneo, E
    PHARMACOLOGICAL RESEARCH, 2005, 52 (02) : 133 - 139
  • [2] Induced Pluripotent Stem Cells in Huntington's Disease: Disease Modeling and the Potential for Cell-Based Therapy
    Liu, Ling
    Huang, Jin-Sha
    Han, Chao
    Zhang, Guo-Xin
    Xu, Xiao-Yun
    Shen, Yan
    Li, Jie
    Jiang, Hai-Yang
    Lin, Zhi-Cheng
    Xiong, Nian
    Wang, Tao
    MOLECULAR NEUROBIOLOGY, 2016, 53 (10) : 6698 - 6708
  • [3] Induced Pluripotent Stem Cells in Huntington’s Disease: Disease Modeling and the Potential for Cell-Based Therapy
    Ling Liu
    Jin-Sha Huang
    Chao Han
    Guo-Xin Zhang
    Xiao-Yun Xu
    Yan Shen
    Jie Li
    Hai-Yang Jiang
    Zhi-Cheng Lin
    Nian Xiong
    Tao Wang
    Molecular Neurobiology, 2016, 53 : 6698 - 6708
  • [4] Stem cell-based therapy for Huntington's disease
    Maucksch, Christof
    Vazey, Elena M.
    Gordon, Renee J.
    Connor, Bronwen
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2013, 114 (04) : 754 - 763
  • [5] Induced Pluripotent Stem Cell-Derived Neural Stem Cell Transplantations Reduced Behavioral Deficits and Ameliorated Neuropathological Changes in YAC128 Mouse Model of Huntington's Disease
    Al-Gharaibeh, Abeer
    Culver, Rebecca
    Stewart, Andrew N.
    Srinageshwar, Bhairavi
    Spelde, Kristin
    Frollo, Laura
    Kolli, Nivya
    Story, Darren
    Paladugu, Leela
    Anwar, Sarah
    Crane, Andrew
    Wyse, Robert
    Maiti, Panchanan
    Dunbar, Gary L.
    Rossignol, Julien
    FRONTIERS IN NEUROSCIENCE, 2017, 11
  • [6] Mesenchymal Stem Cell Transplants Reduce Behavioral Deficits in the R6/2 Mouse Model of Huntington's Disease
    Rossinol, J.
    Fink, K. D.
    Davis, K. K.
    Cheng, S.
    Lowrance, S. A.
    Matchynski, J. J.
    Lescaudron, L.
    Dunbar, G. L.
    CELL TRANSPLANTATION, 2010, 19 (03) : 359 - 359
  • [7] Intrastriatal Transplantation of Mouse Adenovirus-Generated Induced Pluripotent Stem Cells Reduced Behavioral Deficits in the YAC128 Mouse Model of Huntington's Disease
    Gharaibeh, A.
    Culver, R.
    Crane, A.
    Wyse, R.
    Antcliff, A.
    Shall, G.
    Moore, S.
    Srinageshwar, B.
    Kolli, N.
    Story, D.
    Lossia, O.
    Frollo, L.
    Eickholt, A.
    Dunbar, G.
    Rossignol, J.
    CELL TRANSPLANTATION, 2016, 25 (04) : 757 - 758
  • [8] Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease
    Cuesta, Marc
    Aungier, Juliet
    Morton, A. Jennifer
    NEUROBIOLOGY OF DISEASE, 2014, 63 : 85 - 91
  • [9] Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease
    Dey, Nicholas D.
    Bombard, Matthew C.
    Roland, Bartholomew P.
    Davidson, Stacy
    Lu, Ming
    Rossignol, Julien
    Sandstrom, Michael I.
    Skeel, Reid L.
    Lescaudron, Laurent
    Dunbar, Gary L.
    BEHAVIOURAL BRAIN RESEARCH, 2010, 214 (02) : 193 - 200
  • [10] miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models
    Cheng, Pei-Hsun
    Li, Chia-Ling
    Chang, Yu-Fan
    Tsai, Shaw-Jeng
    Lai, Yen-Yu
    Chan, Anthony W. S.
    Chen, Chuan-Mu
    Yang, Shang-Hsun
    AMERICAN JOURNAL OF HUMAN GENETICS, 2013, 93 (02) : 306 - 312