Integrative treatment program for the treatment of children with autism spectrum disorder: A prospective observational case series

被引:1
|
作者
Lee, Boram [1 ]
Park, Serin [2 ]
Kwon, Hyun Jeong [2 ]
Hwang, Gwi Seo [3 ]
Kim, Moonju [4 ]
机构
[1] Korea Inst Oriental Med, KM Sci Res Div, Daejeon, South Korea
[2] Floortime Ctr Korea, Seoul, South Korea
[3] Gachon Univ, Coll Korean Med, Seongnam, South Korea
[4] ITomato Korean Med Clin, Seoul, South Korea
来源
FRONTIERS IN NEUROLOGY | 2023年 / 13卷
关键词
integrative medicine; autism spectrum disorder; herbal medicine; Floortime; sensory enrichment therapy; case series; ENVIRONMENTAL ENRICHMENT; ALTERNATIVE MEDICINE; COMPLEMENTARY; INTERVENTION; INFANTS; TRIAL; RISK;
D O I
10.3389/fneur.2022.1017005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BackgroundIn a situation where conventional treatments for autism spectrum disorder (ASD) are labor-intensive and there are concerns about the side effects of conventional medications, a 6-month integrative treatment program, including herbal medicine (HM), Floortime, and sensory enrichment therapy (SET) has been used on children with ASD in Korean medicine clinical settings. MethodsWe observed the treatment responses of 18 children with ASD (66.7% male, mean age 3.9 +/- 0.9 years) to the integrative treatment program as part of a prospective, single-center, observational case series. Individualized HMs were administered according to the patient's symptoms, and parents were instructed to perform Floortime and SET with their children at home for 2 h and 20 min a day, 5 days a week, respectively. The Childhood Autism Rating Scale (CARS) and Autism Behavior Checklist (ABC) were used to evaluate the core symptoms of ASD. A linear mixed model for repeated measures was used for analyzing the effect of the program over time, and logistic regression used to explore the predictors of treatment response. ResultsThe CARS and ABC scores were significantly improved from 34.58 +/- 6.27 and 69.28 +/- 15.73 at baseline to 28.56 +/- 6.05 and 39.67 +/- 20.36 after 6 months (p < 0.0001, respectively). No serious adverse events (AEs) were reported, and compliance with HM, Floortime, and SET was high at >90%. ConclusionThis 6-month integrative treatment program appears to be a potentially effective, safe, and feasible option for children with ASD. Low baseline CARS scores may be predictors of higher treatment response.
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页数:9
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