Sex- and gender-related disparities in chest pain syndromes: the feminine mystique of chest pain

被引:21
作者
Angeli, Francesco [1 ,2 ]
Ricci, Fabrizio [3 ]
Moscucci, Federica [4 ]
Sciomer, Susanna [5 ]
Bucciarelli, Valentina [6 ]
Bianco, Francesco [6 ]
Mattioli, Anna Vittoria [7 ]
Pizzi, Carmine [1 ,2 ,8 ]
Gallina, Sabina [3 ]
机构
[1] IRCCS Azienda Osped Univ Bologna, Cardiac Thorac & Vasc Dept, Cardiol Unit, Bologna, Italy
[2] Univ Bologna, Dept Med & Surg Sci DIMEC, Via Giuseppe Massarenti 9, I-40138 Bologna, Italy
[3] G D Annunzio Univ Chieti Pescara, Dept Neurosci Imaging & Clin Sci, Chieti, Italy
[4] Policlin Umberto 1, Dept Internal Med & Med Specialties, Viale Policlin n 155, I-00161 Rome, Italy
[5] Sapienza Rome Univ, Dipartimento Sci Clin Internist Anestesiol & Cardi, Viale Univ,37, I-00185 Rome, Italy
[6] Azienda Osped Univ Marche, Cardiovasc Sci Dept, Ancona, Italy
[7] Univ Modena & Reggio Emilia, Dept Med & Surg Sci Children & Adults, Modena, Italy
[8] IRCCS Azienda Osped Univ Bologna, Dept Med & Surg Sci DIMEC, Alma Mater Studiorum, Cardiol Unit,Cardiac Thorac & Vasc Dept, Bologna, Italy
关键词
sex; gender medicine; chest pain; myocardial infarction; PERCUTANEOUS CORONARY INTERVENTION; ACUTE MYOCARDIAL-INFARCTION; CARDIOLOGY WORKING GROUP; MICROVASCULAR DYSFUNCTION; ESC GUIDELINES; CARDIAC PAIN; WOMEN; RISK; MANAGEMENT; DIAGNOSIS;
D O I
10.1016/j.cpcardiol.2024.102457
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chest pain syndromes encompass a wide range of different clinical conditions, being coronary artery disease one of the most important and feared aetiology. Sex and gender disparities have been reported in pathophysiology, clinical presentations, diagnostic work-up and outcomes of patients admitted for chest pain. Biological differences in sexual hormones and neurological pain procession pathways have been proposed as contributors to disparities between men and women; however, gender-related disparities in socio-economic and psychological status have emerged as additional factors involved in these conditions. A better understanding of gender- and sex-related disparities will lead to improved clinical care and management of chest pain syndromes in both men and women. In this comprehensive review, we describe the existing knowledge regarding sex and gender-based differences in management and outcomes of chest pain syndromes in order to stimulate and promote the development of a more sex- and gender-oriented approach to these conditions.
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收藏
页数:11
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