DBN Promoted [4+2] Annulation of Malononitrile and 2-(3-Oxo-3-arylprop-1-en-1-yl)phenyl buta-2,3-dienoates to Construct 2-Amino-4-(2-oxo-2-phenylethyl)-4H-chromene-3-carbonitriles

被引：1

作者：

Sun, Xiaobin ^{[1
]}

Lu, Tianyu ^{[1
]}

Lin, Weisheng ^{[2
]}

Miao, Zhiwei ^{[1
,2
]}

机构：

[1] Nankai Univ, Coll Chem, State Key Lab & Inst Elementoorgan Chem, R China, Tianjin 300071, Peoples R China

[2] Wuyi Univ, Dept Ecol & Resources Engn, Wuyishan 354300, Fujian, Peoples R China

来源：

CHEMISTRYSELECT | 2024年 / 9卷 / 05期

关键词：

cycloaddition; DBN promotion; annulation; Malononitrile; 2-(buta-2,3-dienoicacyl) chalcone; APOPTOSIS INDUCERS; DISCOVERY; SERIES; 4-ARYL-4H-CHROMENES; DERIVATIVES;

D O I：

10.1002/slct.202304606

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A DBN promoted [4+2] cycloaddition of malononitrile with 2-(3-oxo-3-arylprop-1-en-1-yl)phenyl buta-2,3-dienoates has been developed. This protocol provides a simple strategy for the construction of 2-amino-4-(2-oxo-2-phenylethyl)-4H-chromene-3-carbonitriles in moderate to good yields.

引用

页数：5

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