The impact of PM2.5 on kidney

被引:8
作者
Xu, Chunming [1 ,2 ]
Zhang, Qian [1 ,3 ]
Huang, Guochen [1 ,3 ]
Huang, Jia [2 ,4 ]
Zhang, Hongxia [1 ,2 ,3 ]
机构
[1] Weifang Med Univ, Dept Clin Pathol, Weifang, Shandong, Peoples R China
[2] Weifang Med Univ, Neurol Disorders & Regenerat Repair Lab Shandong, Weifang, Shandong, Peoples R China
[3] Weifang Med Univ, Key Lab Immunol Univ Shandong Prov, Weifang, Shandong, Peoples R China
[4] Weifang Med Univ, Dept Histol & Embryol, Weifang, Shandong, Peoples R China
关键词
air pollution; cytotoxicity; inflammatory; kidney injury; oxidative stress; PM2; 5; AMBIENT AIR-POLLUTION; OXIDATIVE STRESS; PARTICULATE MATTER; DNA-DAMAGE; EXPOSURE; HEALTH; APOPTOSIS; CANCER; RISK; INFLAMMATION;
D O I
10.1002/jat.4356
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
PM2.5 poses a severe risk to kidneys, inducing kidney function decline, increasing the risk of suffering from chronic kidney diseases and promoting the occurrence and development of various renal tumors. The mechanism of PM2.5-induced renal injury may involve oxidative stress, inflammatory response, and cytotoxicity. This paper elaborated PM2.5-induced kidney damage and the corresponding possible mechanism so as to raise awareness of air pollution and reduce the damage to human body.
引用
收藏
页码:107 / 121
页数:15
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