Solving the puzzle of fibrosis resolution in alcohol-associated liver disease: An insight from KDM5 demethylases and LXR activation

被引：0
|
作者：
Ma, Jing [1 ,3 ]
Liangpunsakul, Suthat [1 ,2 ]
机构：
[1] Indiana Univ Sch Med, Dept Med, Div Gastroenterol & Hepatol, Indianapolis, IN USA
[2] Richard L Roudebush Vet Adm Med Ctr, Med Serv, Indianapolis, IN USA
[3] Indiana Univ Sch Med, Dept Med, Div Gastroenterol & Hepatol, 702 Rotary Circle, Indianapolis, IN 46202 USA
来源：
HEPATOLOGY | 2024年 / 80卷 / 01期
关键词：
STELLATE CELLS ACTIVATION; INVERSE AGONIST; ABSTINENCE; PROGNOSIS; MODEL;
D O I：
10.1097/HEP.0000000000000781
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：14 / 17
页数：4
相关论文
共 50 条
  • [1] Demethylases KDM5B and KDM5C control cellular crosstalk in alcohol-associated liver disease development and resolution
    Schonfeld, M.
    Weinman, S. A.
    Tikhanovich, I.
    ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 47 : 135 - 135
  • [2] ALCOHOL-ASSOCIATED FIBROSIS IN FEMALES IS MEDIATED BY GENDER SPECIFIC ACTIVATION OF LYSINE DEMETHYLASES KDM5B AND KDM5C
    Schonfeld, M.
    Averilla, J.
    Gunewardena, S.
    Weinman, S. A.
    Tikhanovich, I.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2022, 46 : 52A - 52A
  • [3] Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C
    Schonfeld, Michael
    Averilla, Janice
    Gunewardena, Sumedha
    Weinman, Steven A.
    Tikhanovich, Irina
    HEPATOLOGY COMMUNICATIONS, 2022, 6 (08) : 2042 - 2057
  • [4] Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease
    Mokou, Marika
    Klein, Julie
    Makridakis, Manousos
    Bitsika, Vasiliki
    Bascands, Jean-Loup
    Saulnier-Blache, Jean Sebastien
    Mullen, William
    Sacherer, Michael
    Zoidakis, Jerome
    Pieske, Burkert
    Mischak, Harald
    Roubelakis, Maria G.
    Schanstra, Joost P.
    Vlahou, Antonia
    EBIOMEDICINE, 2019, 41 : 91 - 104
  • [5] GENDER DIFFERENCES IN ALCOHOL-ASSOCIATED LIVER DISEASE ARE MEDIATED BY H3K4 LYSINE DEMETHYLASES KDM5B AND KDM5C
    Schonfeld, Michael
    Averilla, Janice
    Gunewardena, Sumedha
    Weinman, Steven A.
    Tikhanovich, Irina
    HEPATOLOGY, 2021, 74 : 214A - 214A
  • [6] Activation of HSCs in alcohol-associated liver disease
    Kisseleva, T.
    ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 47 : 83 - 83
  • [7] The Integrated "Multiomics" Landscape at Peak Injury and Resolution From Alcohol-Associated Liver Disease
    Das, Sukanta
    Ge, Xiaodong
    Han, Hui
    Desert, Romain
    Song, Zhuolun
    Athavale, Dipti
    Chen, Wei
    Gaskell, Harriet
    Lantvit, Daniel
    Guzman, Grace
    Nieto, Natalia
    HEPATOLOGY COMMUNICATIONS, 2022, 6 (01) : 133 - 160
  • [8] Alcohol-Associated Liver Disease - From Pathogenesis to Treatment
    Singal, Ashwani K.
    Anand, Anil C.
    JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY, 2023, 13 (03) : 387 - 389
  • [9] From intestinal dysbiosis to alcohol-associated liver disease
    Mendes, Beatriz Garcia
    Schnabl, Bernd
    CLINICAL AND MOLECULAR HEPATOLOGY, 2020, 26 (04) : 595 - 605
  • [10] Investigating the C5 complosome in Kupffer cell inflammatory activation in alcohol-associated liver disease
    Twardy, S.
    McCullough., R.
    ALCOHOL, 2024, 121
12345