Comparison of Serum Per- and Polyfluoroalkyl Substances Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits

被引：4

作者：

Nematollahi, Amy J. ^{[1
]}

Fisher, Julia M. ^{[2
]}

Furlong, Melissa A. ^{[1
]}

Beamer, Paloma I. ^{[1
]}

Goodrich, Jaclyn M. ^{[3
]}

Graber, Judith M. ^{[4
]}

Calafat, Antonia M. ^{[5
]}

Botelho, Julianne Cook

Beitel, Shawn C. ^{[1
]}

Littau, Sally R. ^{[1
]}

Gulotta, John J. ^{[6
]}

Wallentine, Darin D. ^{[7
]}

Burgess, Jefferey L. ^{[1
,8
]}

机构：

[1] Univ Arizona, Mel & Enid Zuckerman Sch Publ Hlth, Environm Hlth Sci, Tucson, AZ 85724 USA

[2] Univ Arizona, Inst BIO5, Stat Consulting Lab, Tucson, AZ 85724 USA

[3] Univ Michigan, Sch Publ Hlth, Ann Arbor, MI USA

[4] Rutgers State Univ, Sch Publ Hlth, Piscataway, NJ USA

[5] CDCP, Div Lab Sci, Natl Ctr Environm Hlth, Atlanta, GA USA

[6] Tucson Fire Dept, Tucson, AZ USA

[7] Sarasota Cty Fire Dept, Sarasota, FL USA

[8] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, 1295 N Martin Ave, Tucson, AZ 85724 USA

来源：

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2024年 / 66卷 / 03期

关键词：

PFAS; workplace exposures; vulnerable occupations; PERFLUOROALKYL SUBSTANCES; EXPOSURE; COHORT; ACIDS; PERFLUOROOCTANOATE; MORTALITY; COMMUNITY; CHEMICALS; HEALTH; URINE;

D O I：

10.1097/JOM.0000000000003020

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: Firefighters are occupationally exposed to per- and polyfluoroalkyl substances (PFAS). This study objective was to compare serum PFAS concentrations in incumbent and recruit firefighters and evaluate temporal trends among recruits. Methods: SerumPFAS concentrations weremeasured in 99 incumbent and 55 recruit firefighters at enrollment in 2015-2016, with follow-up 20 to 37 months later for recruits. Linear and logistic regression and linear mixed-effects models were used for analyses. Fireground exposure impact on PFAS concentrations was investigated using adjusted linear and logistic regression models. Results: Incumbents had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits. No significant links were found between cumulative fireground exposures and PFAS concentrations. Conclusions: Serum PFAS concentrations were not increased in incumbent firefighters compared with recruits and were not associated with cumulative fireground exposures.

引用

页码：202 / 211

页数：10

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