Comparison of Serum Per- and Polyfluoroalkyl Substances Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits

被引:2
作者
Nematollahi, Amy J. [1 ]
Fisher, Julia M. [2 ]
Furlong, Melissa A. [1 ]
Beamer, Paloma I. [1 ]
Goodrich, Jaclyn M. [3 ]
Graber, Judith M. [4 ]
Calafat, Antonia M. [5 ]
Botelho, Julianne Cook
Beitel, Shawn C. [1 ]
Littau, Sally R. [1 ]
Gulotta, John J. [6 ]
Wallentine, Darin D. [7 ]
Burgess, Jefferey L. [1 ,8 ]
机构
[1] Univ Arizona, Mel & Enid Zuckerman Sch Publ Hlth, Environm Hlth Sci, Tucson, AZ 85724 USA
[2] Univ Arizona, Inst BIO5, Stat Consulting Lab, Tucson, AZ 85724 USA
[3] Univ Michigan, Sch Publ Hlth, Ann Arbor, MI USA
[4] Rutgers State Univ, Sch Publ Hlth, Piscataway, NJ USA
[5] CDCP, Div Lab Sci, Natl Ctr Environm Hlth, Atlanta, GA USA
[6] Tucson Fire Dept, Tucson, AZ USA
[7] Sarasota Cty Fire Dept, Sarasota, FL USA
[8] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, 1295 N Martin Ave, Tucson, AZ 85724 USA
关键词
PFAS; workplace exposures; vulnerable occupations; PERFLUOROALKYL SUBSTANCES; EXPOSURE; COHORT; ACIDS; PERFLUOROOCTANOATE; MORTALITY; COMMUNITY; CHEMICALS; HEALTH; URINE;
D O I
10.1097/JOM.0000000000003020
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: Firefighters are occupationally exposed to per- and polyfluoroalkyl substances (PFAS). This study objective was to compare serum PFAS concentrations in incumbent and recruit firefighters and evaluate temporal trends among recruits. Methods: SerumPFAS concentrations weremeasured in 99 incumbent and 55 recruit firefighters at enrollment in 2015-2016, with follow-up 20 to 37 months later for recruits. Linear and logistic regression and linear mixed-effects models were used for analyses. Fireground exposure impact on PFAS concentrations was investigated using adjusted linear and logistic regression models. Results: Incumbents had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits. No significant links were found between cumulative fireground exposures and PFAS concentrations. Conclusions: Serum PFAS concentrations were not increased in incumbent firefighters compared with recruits and were not associated with cumulative fireground exposures.
引用
收藏
页码:202 / 211
页数:10
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