Vitamin B12

被引：10

作者：

Wolffenbuttel, Bruce H. R. ^{[1
]}

Owen, P. Julian ^{[2
]}

Ward, Mary ^{[3
]}

Green, Ralph ^{[4
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands

[2] Cambridge Univ Hosp NHS Trust, Dept Trauma & Orthopaed, Addenbrookes, Cambridge, England

[3] Ulster Univ, Nutr Innovat Ctr Food & Hlth, Sch Biomed Sci, Coleraine, North Ireland

[4] Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA USA

来源：

BMJ-BRITISH MEDICAL JOURNAL | 2023年 / 383卷

关键词：

COBALAMIN; DEFICIENCY; DISORDERS; TRANSCOBALAMIN; ASSOCIATIONS; HAPTOCORRIN; GUIDELINES; DIAGNOSIS; PATIENT; RISKS;

D O I：

10.1136/bmj-2022-071725

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

What is vitamin B12? Vitamin B12 (cobalamin) is a water soluble vitamin required for several physiological processes, including normal nervous system functioning, and red blood cell development and maturation. It has antioxidant effects, is a co-factor in mitochondrial energy metabolism, and contributes to DNA synthesis, the methylation cycle, and epigenetic regulation.1 2 B12 is present in foods of animal origin, such as meat, eggs, and milk, or via food fortification. Healthy adults require an average intake of 4-7 mcg daily to maintain B12 status.3 4 Indications for B12 treatment, administration routes, and preparations Treatment with B12 may be required for a variety of reasons (table 1). © 2023 BMJ Publishing Group. All rights reserved.

引用

页数：8

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