A rare case of acute eosinophilic pneumonia induced by vaping-associated lung injury: a case report

BackgroundAcute eosinophilic pneumonia (AEP) is well-known as one of the primary eosinophilic pulmonary diseases of unknown etiology. It's defined as a febrile illness along with acute onset respiratory failure that is commonly misdiagnosed at the initial presentation as infectious pneumonia. Despite the fact that AEP sometimes classified as idiopathic as no exact cause can be identified in most cases, it has been suggested recently to be linked with electronic cigarette or vaping products and associated with electronic cigarette or vaping associated lung injury (EVALI). Therefore, history of recent tobacco smoking or vaping exposure along with peripheral eosinophilia are crucial clinical findings suggestive of AEP.Case presentationA previously healthy 17-year-old female presented to the Emergency Room with one day history of progressively worsening shortness of breath accompanied by left sided pleuritic chest pain and fever. She wasn't taking any medications, denied traditional cigarette smoking, exposure to pulmonary irritants, recent travel and had no history of close contact with sick patient. She recently started vaping 20 days prior to the presentation. Initially, she was admitted with a presumptive diagnosis of atypical pneumonia but was found to have AEP due to a recent vaping exposure.ConclusionVaping is a well-known health hazard that has become a growing trend among adolescents and have been promoted as a safe and effective alternative to traditional cigarettes. The etiology of AEP remains unclear, but many studies suggest a possible link with recent tobacco smoking or vaping. A key challenge for this clinical entity is to reach the diagnosis after excluding all other pulmonary eosinophilia causes, and it has an excellent prognosis if diagnosed early and treated appropriately. Established Facts & BULL; The eosinophilic lung diseases (ELD) are a diverse group of pulmonary conditions associated with peripheral or tissue eosinophilia.& BULL; Acute eosinophilic pneumonia (AEP) is an extremely rare disorder characterized by nonproductive cough, dyspnea, and fever that typically present in less than four weeks.& BULL; The cause of AEP is unknown, but several factors are necessary for the development of the disorder, with association of a triggering factor in a predisposed individual.Novel Insights & BULL; The association of AEP with recent tobacco smoking or vaping exposure suggests a possible link.& BULL; The treatment of AEP depends on the underlying cause when recognized, but glucocorticoids are the treatment of choice when it is caused by noninfectious causes.& BULL; Prognosis of AEP is excellent if treated appropriately with corticosteroids.