Regiodivergent C-H Annulation of Imines with Unsymmetrical Alkynes Using Transient Directing Alcohols via Rh(III) Catalysis

被引：6

作者：

Liu, Bairong ^{[1
]}

Chen, Yabo ^{[1
]}

Liang, Qixin ^{[1
]}

Liang, Yuyao ^{[1
]}

Liu, Bifu ^{[2
]}

Liu, Yuan ^{[1
]}

Gao, Yang ^{[1
]}

Chen, Qian ^{[1
]}

Huo, Yanping ^{[1
]}

Li, Xianwei ^{[1
]}

机构：

[1] Guangdong Univ Technol, Sch Chem Engn & Light Ind, Guangzhou 510006, Peoples R China

[2] Huizhou Univ, Sch Chem & Mat Engn, Huizhou 516007, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2023年 / 365卷 / 12期

基金：

美国国家科学基金会;

关键词：

regioselectivity; unsymmetrical alkynes; transformable directing groups; dual and triple C-H annulation; fused rings; N BOND FORMATION; AROMATIC KETIMINES; PROPARGYL ALCOHOLS; ORTHO-ALKENYLATION; INTERNAL ALKYNES; ACTIVATION; FUNCTIONALIZATION; HYDROARYLATION; CYCLOADDITION; BENZAMIDES;

D O I：

10.1002/adsc.202300167

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Regiodivergent [3+2] and [4+2] C-H annulation of imines and imidate esters with unsymmetrical alkynes has been achieved under Rh(III) catalysis. Further transformation of the aldehyde and TMS functionality on the indene products is also demonstrated. The current work highlights the alcohols-directed multiple C-H annulation of imines and imidate esters, leading to diverse fused heterocycles.

引用

页码：2018 / 2025

页数：8

共 91 条

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