Engineering cell-derived extracellular vesicles for gene therapy

被引：0
|
作者：
Stranford, Devin [1 ]
Leonard, Joshua [1 ]
机构：
[1] Northwestern Univ, Evanston, IL 60208 USA
来源：
NATURE BIOMEDICAL ENGINEERING | 2024年 / 8卷 / 04期
关键词：
D O I：
10.1038/s41551-023-01167-2
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Many genetic therapies are limited by a lack of methods for delivering them to target cells in the body. We have developed technologies to engineer biological nanovesicles to load therapeutic proteins, target recipient immune cells and deliver Cas9 to knock out CXCR4 in primary human T cells.
引用
收藏
页码：343 / 344
页数：2
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