Pharmacokinetics of cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside after intravenous administration in rats

被引：2
|
作者：
Chen, Yan [1 ]
Zhao, Jing [1 ]
Li, Han-Han [1 ]
Qian, Wen [2 ]
Zhou, Bing-Yu [3 ]
Yang, Chang-Qing [1 ]
机构：
[1] China Pharmaceut Univ, Sch Basic Med & Clin Pharm, Nanjing 210000, Peoples R China
[2] Nanjing BRT Biomed Co Ltd, Nanjing 210000, Peoples R China
[3] Dongliao Peoples Hosp, Dept Pharm, Liaoyuan 136200, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年 / 26卷 / 06期
关键词：
Cyanidin-3-O-galactoside; cyanidin-3-O-arabinoside; pharmacokinetics; HPLC; black chokeberry; ARONIA-MELANOCARPA; TISSUE DISTRIBUTION; ANTHOCYANINS; BIOAVAILABILITY; ANTIOXIDANT; EXTRACTS;
D O I：
10.1080/10286020.2023.2279541
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside (purity >98%) were isolated from black chokeberry by preparative high-performance liquid chromatography, and an animal experiment was conducted to investigate the pharmacokinetics of two anthocyanin monomers after intravenous administration. The results showed that cyanidin-3-O-galactoside has preferable druggability than cyanidin-3-O-arabinoside in pharmacokinetic area. [GRAPHICS]
引用
收藏
页码：714 / 725
页数：12
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