Pharmacokinetics of cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside after intravenous administration in rats

被引：2

作者：

Chen, Yan ^{[1
]}

Zhao, Jing ^{[1
]}

Li, Han-Han ^{[1
]}

Qian, Wen ^{[2
]}

Zhou, Bing-Yu ^{[3
]}

Yang, Chang-Qing ^{[1
]}

机构：

[1] China Pharmaceut Univ, Sch Basic Med & Clin Pharm, Nanjing 210000, Peoples R China

[2] Nanjing BRT Biomed Co Ltd, Nanjing 210000, Peoples R China

[3] Dongliao Peoples Hosp, Dept Pharm, Liaoyuan 136200, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年 / 26卷 / 06期

关键词：

Cyanidin-3-O-galactoside; cyanidin-3-O-arabinoside; pharmacokinetics; HPLC; black chokeberry; ARONIA-MELANOCARPA; TISSUE DISTRIBUTION; ANTHOCYANINS; BIOAVAILABILITY; ANTIOXIDANT; EXTRACTS;

D O I：

10.1080/10286020.2023.2279541

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside (purity >98%) were isolated from black chokeberry by preparative high-performance liquid chromatography, and an animal experiment was conducted to investigate the pharmacokinetics of two anthocyanin monomers after intravenous administration. The results showed that cyanidin-3-O-galactoside has preferable druggability than cyanidin-3-O-arabinoside in pharmacokinetic area. [GRAPHICS]

引用

页码：714 / 725

页数：12

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