Equine Bone Marrow Aspirate Concentrate

被引：3

作者：

Fortier, Lisa A. ^{[1
,2
]}

机构：

[1] Cornell Univ, Coll Vet Med, Clin Sci, Ithaca, NY USA

[2] 931 North Meacham Rd,Suite 100, Schaumburg, IL 60173 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE | 2023年 / 39卷 / 03期

关键词：

Bone marrow concentrate; BMAC; Bone marrow; cBMA; Equine; PLATELET-RICH PLASMA; STERNUM; CARTILAGE; RECOVERY;

D O I：

10.1016/j.cveq.2023.05.002

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The generation of BMC requires a bit more technical expertise and time to obtain the BMA compared to obtaining blood to generate PRP, but otherwise the equipment required to generate either biologic is similar. However, the presence of MSC, IL-1RA, and increased anabolic growth factors in BMC compared to PRP should also be considered when choosing the optimal biologic for the patient. Clinical application of BMC should be considered for enhanced cartilage defect repair, alleviation of symptomatic osteoarthritis, bone regeneration particularly in cystic lesions, and suspensory desmitis.

引用

页码：453 / 459

页数：7

共 28 条

[1] Equine bone marrow-derived mesenchymal stromal cells (BMDMSCs) from the ilium and sternum: Are there differences? [J].

Adams, M. K. ;

Goodrich, L. R. ;

Rao, S. ;

Olea-Popelka, F. ;

Phillips, N. ;

Kisiday, J. D. ;

McIlwraith, C. W. .

EQUINE VETERINARY JOURNAL, 2013, 45 (03) :372-375

[2] Comparison of Techniques for Preimplantation Treatment of Osteochondral Allograft Bone [J].

Baumann, Charles A. ;

Baumann, John R. ;

Bozynski, Chantelle C. ;

Stoker, Aaron M. ;

Stannard, James P. ;

Cook, James L. .

JOURNAL OF KNEE SURGERY, 2019, 32 (01) :97-104

[3] Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration [J].

Cassano, Jennifer M. ;

Kennedy, John G. ;

Ross, Keir A. ;

Fraser, Ethan J. ;

Goodale, Margaret B. ;

Fortier, Lisa A. .

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2018, 26 (01) :333-342

[4] Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment [J].

Cassano, Jennifer M. ;

Schnabel, Lauren, V ;

Goodale, Margaret B. ;

Fortier, Lisa A. .

STEM CELL RESEARCH & THERAPY, 2018, 9

[5] The immunomodulatory function of equine MSCs is enhanced by priming through an inflammatory microenvironment or TLR3 ligand [J].

Cassano, Jennifer M. ;

Schnabel, Lauren V. ;

Goodale, Margaret B. ;

Fortier, Lisa A. .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2018, 195 :33-39

[6]

Cercone M, 2021, Journal of Cartilage & Joint Preservation, V1

[7] Biologic Augmentation for the Operative Treatment of Osteochondral Defects of the Knee: A Systematic Review [J].

Chona, Deepak, V ;

Kha, Stephanie T. ;

Minetos, Paul D. ;

LaPrade, Christopher M. ;

Chu, Constance R. ;

Abrams, Geoffrey D. ;

Safran, Marc R. ;

Sherman, Seth L. .

ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE, 2021, 9 (11)

[8] Biological Mechanisms for Cartilage Repair Using a BioCartilage Scaffold: Cellular Adhesion/Migration and Bioactive Proteins [J].

Commins, Jacqueline ;

Irwin, Rebecca ;

Matuska, Andrea ;

Goodale, Margaret ;

Delco, Michelle ;

Fortier, Lisa .

CARTILAGE, 2021, 13 (1_SUPPL) :984S-992S

[9] Treatment of simple bone cyst with bone marrow concentrate and equine-derived demineralized bone matrix injection versus methylprednisolone acetate injections: A retrospective comparative study [J].

D'Amato, Raffaele Dario ;

Memeo, Antonio ;

Fusini, Federico ;

Panuccio, Elena ;

Peretti, Giuseppe .

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, 2020, 54 (01) :49-58

[10]

Delling U, 2012, CAN J VET RES, V76, P52

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