Advances in PET/CT Imaging for Breast Cancer

被引:8
作者
de Jong, Dorine [1 ]
Desperito, Elise [2 ]
Al Feghali, Karine A. [3 ]
Dercle, Laurent [2 ]
Seban, Romain-David [4 ,5 ]
Das, Jeeban P. [6 ]
Ma, Hong [2 ]
Sajan, Abin [2 ]
Braumuller, Brian [2 ]
Prendergast, Conor [2 ]
Liou, Connie [2 ]
Deng, Aileen [7 ]
Roa, Tina [2 ]
Yeh, Randy [6 ]
Girard, Antoine [8 ]
Salvatore, Mary M. [2 ]
Capaccione, Kathleen M. [2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Ctr Cell Engn, New York, NY 10065 USA
[2] Columbia Univ, Dept Radiol, Irving Med Ctr, New York, NY 10032 USA
[3] RefleXion Med Inc, Hayward, CA 94545 USA
[4] Inst Curie, Dept Nucl Med & Endocrine Oncol, F-92210 St Cloud, France
[5] Paris Sci & Lettres PSL Res Univ, Inst Curie, Lab Translat Imaging Oncol, F-91401 Orsay, France
[6] Mem Sloan Kettering Canc Ctr, Dept Radiol, New York, NY 10065 USA
[7] Novant Hlth, Dept Hematol & Oncol, 170 Med Pk Rd, Mooresville, NC 28117 USA
[8] Univ Rennes 1, Ctr Eugene Marquis, Dept Nucl Med, F-35000 Rennes, France
关键词
breast cancer; triple negative breast cancer (TNBC); F-18-FDG; PET radiotracers; GROWTH-FACTOR RECEPTOR; HISTONE DEACETYLASE INHIBITORS; FIBROBLAST ACTIVATION PROTEIN; TISSUE FACTOR EXPRESSION; ANTIBODY-DRUG CONJUGATE; DIFFERENTIAL EXPRESSION; DOUBLE-BLIND; FACTOR-VIIA; IMMUNO-PET; MONOCLONAL-ANTIBODY;
D O I
10.3390/jcm12134537
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of F-18-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient's specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.
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页数:24
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