New approaches in childhood asthma treatment

被引：6
作者：
Castagnoli, Riccardo [1 ,2 ]
Brambilla, Ilaria [1 ,2 ]
Giovannini, Mattia [3 ,4 ,5 ]
Marseglia, Gian Luigi [1 ,2 ]
Licari, Amelia [1 ,2 ]
机构：
[1] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, Pediat Unit, Pavia, Italy
[2] Fdn IRCCS Policlin San Matteo, Pediat Clin, Pavia, Italy
[3] Meyer Childrens Hosp IRCCS, Allergy Unit, Florence, Italy
[4] Univ Florence, Dept Hlth Sci, Florence, Italy
[5] Univ Florence, Meyer Childrens Hosp IRCCS, Dept Hlth Sci, Allergy Unit, Viale Pieraccini 24, I-50139 Florence, Italy
来源：
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2023年 / 23卷 / 04期
关键词：
asthma; biologics; children; therapy; DOUBLE-BLIND; CHILDREN; OMALIZUMAB; THERAPY; TEZEPELUMAB; BENRALIZUMAB; MALIGNANCY; RECEPTOR; SAFETY; ADULTS;
D O I：
10.1097/ACI.0000000000000922
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Purpose of reviewThis review aims to summarize the most recent advances in asthma management, focusing on novel approaches to pediatric asthma.Recent findingsIn recent years, the therapeutic tools for pediatric asthma have expanded significantly for both the nonsevere and severe forms. The use of anti-inflammatory treatment, even for the mildest cases, and the withdrawal of symptomatic bronchodilation as monotherapy have been included in the most recent guidelines. Also, different biological therapies have revolutionized the therapeutical approach for severe uncontrolled asthma in children and adolescents.With the expanding landscape of novel therapeutic approaches for pediatric asthma, further evidence is needed to help clinicians choose the best option for patients, particularly those with severe asthma. The identification of novel predictive biomarkers may also help pediatricians in selecting children and adolescents for innovative therapies.
引用
收藏
页码：319 / 326
页数：8
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