Migraine headache and aura induced by hypoxia

被引：2
作者：
Al-Karagholi, Mohammad Al-Mahdi [1 ]
Arngrim, Nanna [2 ]
Ashina, Messoud [1 ,3 ,4 ]
机构：
[1] Copenhagen Univ Hosp, Rigshosp, Danish Headache Ctr, Dept Neurol, Copenhagen, Denmark
[2] Odense Univ Hosp, Dept Neurol, Odense, Denmark
[3] Danish Knowledge Ctr Headache Disorders, Glostrup, Denmark
[4] Copenhagen Univ Hosp, Rigshosp, Danish Headache Ctr, Dept Neurol, Valdemar Hansen Vej 5, DK-2600 Glostrup, Denmark
来源：
JOURNAL OF PHYSIOLOGY-LONDON | 2024年 / 602卷 / 21期
关键词：
cortical spreading depolarization; human; K-ATP channel; pathophysiology; CORTICAL SPREADING DEPRESSION; HIGH-ALTITUDE HEADACHE; ENERGY-METABOLISM; NITRIC-OXIDE; BRAIN; ACTIVATION; PREVALENCE; DEPOLARIZATIONS; VASODILATION; SUMATRIPTAN;
D O I：
10.1113/JP284553
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Migraine, a common neurological disorder, impacts over a billion individuals globally. Its complex aetiology involves various signalling cascades. Hypoxia causes headaches such as high-altitude headache and acute mountain sickness which share phenotypical similarities with migraine. Epidemiological data indicate an increased prevalence of migraine with and without aura in high-altitude populations. Experimental studies have further shown that hypoxia can induce migraine attacks. This review summarizes evidence linking hypoxia to migraine, delves into potential pathophysiological mechanisms and highlights research gaps.
引用
收藏
页码：5515 / 5522
页数：8
相关论文
共 57 条
[1]   Targeting CGRP pathways and aura: A peripheral site with a central effect [J].
Al-Karagholi, Mohammad Al-Mahdi .
CEPHALALGIA, 2023, 43 (12)
[2]   Opening of ATP sensitive potassium channels causes migraine attacks with aura [J].
Al-Karagholi, Mohammad Al-Mahdi ;
Ghanizada, Hashmat ;
Nielsen, Cherie Amalie Waldorff ;
Hougaard, Anders ;
Ashina, Messoud .
BRAIN, 2021, 144 :2322-2332
[3]   Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine [J].
Al-Karagholi, Mohammad Al-Mahdi ;
Hansen, Jakob Moller ;
Guo, Song ;
Olesen, Jes ;
Ashina, Messoud .
BRAIN, 2019, 142 :2644-2654
[4]   The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine [J].
Al-Karagholi, Mohammad Al-Mahdi ;
Hansen, Jakob Moller ;
Severinsen, Johanne ;
Jansen-Olesen, Inger ;
Ashina, Messoud .
JOURNAL OF HEADACHE AND PAIN, 2017, 18
[5]   Effect of hypoxia on BOLD fMRI response and total cerebral blood flow in migraine with aura patients [J].
Arngrim, Nanna ;
Hougaard, Anders ;
Schytz, Henrik W. ;
Vestergaard, Mark B. ;
Britze, Josefine ;
Amin, Faisal Mohammad ;
Olsen, Karsten S. ;
Larsson, Henrik B. W. ;
Olesen, Jes ;
Ashina, Messoud .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 (04) :680-689
[6]   Migraine induced by hypoxia: an MRI spectroscopy and angiography study [J].
Arngrim, Nanna ;
Schytz, Henrik Winther ;
Britze, Josefine ;
Amin, Faisal Mohammad ;
Vestergaard, Mark Bitsch ;
Hougaard, Anders ;
Wolfram, Frauke ;
de Koning, Patrick J. H. ;
Olsen, Karsten S. ;
Secher, Niels H. ;
Larsson, Henrik Bo Wiberg ;
Olesen, Jes ;
Ashina, Messoud .
BRAIN, 2016, 139 :723-737
[7]   HIGH PREVALENCE OF MIGRAINE IN A HIGH-ALTITUDE POPULATION [J].
ARREGUI, A ;
CABRERA, J ;
LEONVELARDE, F ;
PAREDES, S ;
VISCARRA, D ;
ARBAIZA, D .
NEUROLOGY, 1991, 41 (10) :1668-1670
[8]   Migraine: epidemiology and systems of care [J].
Ashina, Messoud ;
Katsarava, Zaza ;
Thien Phu Do ;
Buse, Dawn C. ;
Pozo-Rosich, Patricia ;
Ozge, Aynur ;
Krymchantowski, Abouch, V ;
Lebedeva, Elena R. ;
Ravishankar, Krishnamurthy ;
Yu, Shengyuan ;
Sacco, Simona ;
Ashina, Sait ;
Younis, Samaira ;
Steiner, Timothy J. ;
Lipton, Richard B. .
LANCET, 2021, 397 (10283) :1485-1495
[9]   Migraine: disease characterisation, biomarkers, and precision medicine [J].
Ashina, Messoud ;
Terwindt, Gisela M. ;
Al-Karagholi, Mohammad Al-Mahdi ;
de Boer, Irene ;
Lee, Mi Ji ;
Hay, Debbie L. ;
Schulte, Laura H. ;
Hadjikhani, Nouchine ;
Sinclair, Alexandra J. ;
Ashina, Hakan ;
Schwedt, Todd J. ;
Goadsby, Peter J. .
LANCET, 2021, 397 (10283) :1496-1504
[10]   Migraine [J].
Ashina, Messoud .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (19) :1866-1876
123456