A NIR turn-on fluorescent probe for specific recognition of cysteine and its application in cells and zebrafish

被引：5
|
作者：
Zhang, Meng [1 ]
Zhang, Yongbin [2 ]
Huo, Fangjun [2 ]
Chao, Jianbin [3 ]
Shuang, Shaomin [1 ]
机构：
[1] Shanxi Univ, Sch Chem & Chem Engn, Taiyuan 030006, Peoples R China
[2] Shanxi Univ, Res Inst Appl Chem, Taiyuan 030006, Peoples R China
[3] Shanxi Univ, Sci Instrument Ctr, Taiyuan 030006, Peoples R China
来源：
DYES AND PIGMENTS | 2023年 / 208卷
基金：
中国国家自然科学基金;
关键词：
Fluorescent probe; Turn-on; Cysteine; Near-infrared; Bioimaging;
D O I：
10.1016/j.dyepig.2022.110774
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new turn-on fluorescent probe (DC-O-SBD) for cysteine (Cys) with a large Stokes shift was synthesized. Free DC-O-SBD had almost no fluorescence. After reacting with Cys, it released near-infrared (NIR) fluorescence at 655 nm. DC-O-SBD can respond to Cys quickly and had high specificity for Cys. Moreover, DC-O-SBD had a low detection limit (0.16 mu M) and a large Stokes shift (155 nm). In addition, DC-O-SBD can efficiently detect Cys in HeLa cells and zebrafish.
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收藏
页数：7
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