An Incidental Finding of a Glucagon-Like Peptide 1 (GLP-1)-Induced Acute Kidney Injury: A Case Report

被引:3
作者
Espino, Andy Aleman [1 ]
Espino, Erik Aleman [1 ]
Oliva, Claudia Aleman [1 ]
Monteagudo, Hamlet [2 ]
Frontela, Odalys [3 ]
机构
[1] Nova Southeastern Univ, Dr Kiran C Patel Coll Osteopath Med, Ft Lauderdale, FL USA
[2] Larkin Community Hosp Palm Springs Campus, Internal Med, Hialeah, FL USA
[3] Larkin Community Hosp, Internal Med, Hialeah, FL 33012 USA
关键词
Categories; Emergency Medicine; Internal Medicine; Nephrology acute kidney injury; clinical case report; glp-1 receptor agonist; general nephrology; acute interstitial nephritis (ain);
D O I
10.7759/cureus.45261
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute kidney injury (AKI) involves a rapid decline in kidney function, classified into prerenal, intrarenal, and postrenal causes. Drug-induced AKI's complex pathophysiology includes altered hemodynamics, inflammation, crystal deposition, hemolysis, and rhabdomyolysis. This report details a 42-year-old female with hypertension and diabetes who, following a dog bite, exhibited reduced kidney function (GFR: 16 mL/min/1.73m2; BUN/Cr: 23/3.23 mg/dL). A renal ultrasound revealed no stones or masses, and the recent use of tirzepatide was identified. Discontinuation of the drug, IV fluid maintenance, and close monitoring led to swift kidney function improvement. This case underscores the importance of recognizing drug-induced AKI, even in unrelated complaints, and highlights the need for vigilance and research into the adverse effects of medications such as glucagon-like peptide 1 (GLP-1) receptor agonists.
引用
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页数:5
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