Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient

被引:2
作者
Shimizu, Kazuhiro [1 ,3 ]
Tabata, Tsuyoshi [2 ]
Iwakawa, Masahiro [1 ]
Sato, Shuji [1 ]
Kinoshita, Toshio [1 ,2 ]
机构
[1] Toho Univ, Div Cardiovasc Med, Dept Internal Med, Sakura Med Ctr, Chiba, Japan
[2] Toho Univ, Sakura Med Ctr, Dept Gastroenterol, Chiba, Japan
[3] Toho Univ, Sakura Med Ctr, Dept Internal Med, 564-1 Shimoshizu, Sakura, Chiba 2858741, Japan
来源
INTERNATIONAL MEDICAL CASE REPORTS JOURNAL | 2023年 / 16卷
关键词
hypertension; angiotensin receptor-neprilysin inhibitor; arterial stiffness; cardio ankle vascular index; CARDIOVASCULAR INTERACTION; CHAMBER QUANTIFICATION; EUROPEAN-ASSOCIATION; AMERICAN-SOCIETY; ECHOCARDIOGRAPHY; NEPRILYSIN; RECOMMENDATIONS; INHIBITOR; STIFFNESS; RECEPTOR;
D O I
10.2147/IMCRJ.S422196
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 72-year-old man presented to our clinic with hypertension. Arterial stiffness evaluated by cardio ankle vascular index (CAVI) was markedly increased at 13.5. We treated him using 80 mg/day of valsartan for three months. CAVI was decreased from 13.5 to 13.0. However, his BP fluctuations were still high. We changed the treatment to angiotensin receptor-neprilysin inhibitor (ARNI) with increasing doses up to 400 mg. Independent of the change in blood pressure at the time of measurement, CAVI improved with ARNI dose. Hypertension treatment with an awareness of the cardio-vascular interaction might be a possibility prevents future heart failure development effectively.
引用
收藏
页码:461 / 465
页数:5
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