Early changes of ganglion cell-inner plexiform layer thickness and macular microvasculature in Posner-Schlossman syndrome: a binocular control study by OCTA

被引:1
作者
Hu, Zhiyi [1 ]
Zhu, Liwei [2 ]
Xu, Junli [2 ]
Wei, Jiamin [2 ]
Wu, Shuangqing [3 ]
Dai, Qi [3 ]
Xu, Qibin [2 ]
机构
[1] Zhejiang Chinese Med Univ, Clin Med Coll 2, Hangzhou, Zhejiang, Peoples R China
[2] Hangzhou Red Cross Hosp, Zhejiang Med & Western Med Integrated Hosp, Dept Ophthalmol, Hangzhou, Zhejiang, Peoples R China
[3] Wenzhou Med Univ, Eye Hosp, Natl Clin Res Ctr Ocular Dis, Wenzhou, Zhejiang, Peoples R China
关键词
Posner-Schlossman syndrome (PSS); optical coherence tomography angiography (OCTA); macular ganglion cell-inner plexiform layer (mGCIPL); macular superficial microvasculature; vessel density (VD); perfusion density (PD); OPTICAL COHERENCE TOMOGRAPHY; OPEN-ANGLE GLAUCOMA; NERVE-FIBER LAYER; VESSEL DENSITY; PERIPAPILLARY; ANGIOGRAPHY;
D O I
10.3389/fmed.2023.1169504
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To evaluate the early changes in ganglion cell-inner plexiform layer thickness and macular microvasculature in Posner-Schlossman syndrome (PSS) with a binocular control study involving optical coherence tomography angiography (OCTA). Twenty-six patients with unilateral PSS were included in this cross-sectional study. All subjects underwent a thorough ocular examination. Macular ganglion cell-inner plexiform layer (mGCIPL) and superficial macular microvasculature measurements, including vessel density (VD), perfusion density (PD) and the foveal avascular zone (FAZ), were recorded. In PSS-affected eyes, the mGCIPL thickness was significantly lower in all quadrants than in the contralateral eyes (all p < 0.05). Significant macular microvascular damage was found in the PSS-affected eyes, including whole-image VD (wiVD), wiPD, perifoveal VD (periVD) and periPD (all p < 0.05); but there was no obvious difference in parafoveal VD (paraVD), paraPD and FAZ parameters (all p > 0.05). In addition, a decreased wiVD and wiPD were significantly correlated with a smaller mGCIPL thickness and a decreased MD (all p < 0.05). These parameters may contribute to the early detection of glaucomatous damage and timely supervision of disease progression in PSS.
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页数:7
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