The association between periodontal disease and risk of adverse maternal or neonatal outcomes: A systematic review and meta-analysis of analytical observational studies

被引:5
作者
Karimi, Newsha [1 ]
Samiee, Negin [2 ]
Moradi, Yousef [3 ]
机构
[1] Kurdistan Univ Med Sci, Student Res Comm, Fac Dent, Sanandaj, Iran
[2] Kurdistan Univ Med Sci, Oral & Maxillofacial Med Dept, Fac Dent, Sanandaj, Iran
[3] Kurdistan Univ Med Sci, Res Inst Hlth Dev, Social Determinant Hlth Res Ctr, Sanandaj, Iran
关键词
maternal outcomes; meta-analysis; neonatal outcomes; periodontal disease; GESTATIONAL DIABETES-MELLITUS; PREGNANCY OUTCOMES; PORPHYROMONAS-GINGIVALIS; PREECLAMPSIA; WOMEN; HETEROGENEITY; HISTORY;
D O I
10.1002/hsr2.1630
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background and Aim: The aim of this meta-analysis was to find the association between periodontal disease (PD) and the risk of adverse pregnancy outcomes, including Pre-eclampsia (PE), premature rupture of the amniotic sac, gestational diabetes (GDM), or low birth weight (LBW) in pregnant women, which should be investigated in a systematic meta-analysis.Methods: Studies that reported the association between PD and pregnancy or neonatal outcomes and were published from January 1990 to December 2022, were identified by an extensive search in PubMed (Medline), Scopus, Web of Sciences, and Medline (Elsevier). After retrieving the studies, the screening stage was performed based on their titles, abstracts, and full texts, and after selecting the final articles, their information was extracted and their quality was assessed using the Newcastle Ottawa Scale checklist.Results: Pregnant women with PD had a 1.39 higher chance of developing GDM than those who did not have the infection (risk ratio [RR]: 1.39; 95% confidence interval [CI]: 1.21-1.61; I square: 49.67%; p: 0.03). Additionally, the pooled RR of LBW was 2.19, which indicates that pregnant women with PD had a 2.19-fold higher risk of LBW than pregnant women who do not have the infection (RR: 2.19; 95% CI: 1.82-2.64; I square: 0.00%; p: 0.65). The relationship between the risk of PE and the existence of PD was examined in 33 cohort and case-control studies for this meta-analysis. These results were combined, and the pooled RR was 1.43. This indicates that pregnant women with PD are 1.43 times more likely to experience PE than pregnant women without PD (RR: 1.43; 95% CI: 1.32-1.54; I square: 82.64%; p: 0.00).Conclusion: According to the findings of the current meta-analysis, PD may contribute to a higher risk of poor maternal and newborn outcomes in pregnant women.
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页数:15
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共 51 条
[1]   Periodontal disease surveillance [J].
Albandar, Jasim M. .
JOURNAL OF PERIODONTOLOGY, 2007, 78 (07) :1179-1181
[2]   Destructive periodontal disease in adults 30 years of age and older in the United states, 1988-1994 [J].
Albandar, JM ;
Brunelle, JA ;
Kingman, A .
JOURNAL OF PERIODONTOLOGY, 1999, 70 (01) :13-29
[3]   The influence of periodontitis case definition on the association between periodontal disease and glycaemic status [J].
Alhassani, Ahmed A. .
COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY, 2023, 51 (06) :1100-1108
[4]  
Baeza M, 2020, J APPL ORAL SCI, V28
[5]   Periodontitis and Gestational Diabetes Mellitus: A Potential Inflammatory Vicious Cycle [J].
Bendek, Maria Jose ;
Canedo-Marroquin, Gisela ;
Realini, Ornella ;
Retamal, Ignacio N. ;
Hernandez, Marcela ;
Hoare, Anilei ;
Busso, Dolores ;
Monteiro, Lara J. ;
Illanes, Sebastian E. ;
Chaparro, Alejandra .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
[6]   Oral bacteria in placental tissues: increased molecular detection in pregnant periodontitis patients [J].
Blanc, V. ;
O'Valle, F. ;
Pozo, E. ;
Puertas, A. ;
Leon, R. ;
Mesa, F. .
ORAL DISEASES, 2015, 21 (07) :905-912
[7]   Association between gestational diabetes mellitus and periodontitis via the effect of reactive oxygen species in peripheral blood cells [J].
Bunpeng, Nattawan ;
Boriboonhirunsarn, Dittakarn ;
Boriboonhirunsarn, Chatkoew ;
Sawangpanyangkura, Teerat ;
Tansriratanawong, Kallapat .
JOURNAL OF PERIODONTOLOGY, 2022, 93 (05) :758-769
[8]  
Carta G, 2004, Clin Exp Obstet Gynecol, V31, P47
[9]   Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and-9 are associated with the severity of periodontitis and the development of gestational diabetes mellitus [J].
Chaparro, Alejandra ;
Realini, Ornella ;
Hernandez, Marcela ;
Albers, Daniela ;
Weber, Laura ;
Ramirez, Valeria ;
Param, Fernanda ;
Kusanovic, Juan Pedro ;
Sorsa, Timo ;
Rice, Gregory Edward ;
Illanes, Sebastian E. .
JOURNAL OF PERIODONTOLOGY, 2021, 92 (02) :205-215
[10]   Relationship between periodontal disease and gestational diabetes mellitus: A systematic review [J].
Charnaud, S. ;
Szonyi, V. ;
Grosgogeat, B. ;
Gritsch, K. .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2022, 186