Efficiency of the allergological study in the diagnosis of allergic reactions to beta-lactams

被引:0
|
作者
Bote, M. D. Rodriguez [1 ]
Cereijo, L. Dominguez [1 ]
Alcaniz, A. Conde [1 ]
Martinez, Guardia [1 ]
机构
[1] Hosp Univ Virgen Macarena, Serv Alergol, Seville, Spain
来源
MEDICINA DE FAMILIA-SEMERGEN | 2023年 / 49卷 / 01期
关键词
Antibiotics; Allergy; beta-lactam; Label; Profitability; Microbial resistance; Health spending; REPORTED PENICILLIN ALLERGY; HYPERSENSITIVITY REACTIONS; CHILDREN; IMPACT;
D O I
10.1016/j.semerg.2022.101866
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Aims: Assessing the rate of beta-lactams-allergic patients who are still labelled as such in their medical records after being performed an allergic test; as well as the rate of no allergic patients who were prescribed one of these antibiotics; and pondering whether the allergic test is hence cost-effective.Methods: This is a retrospective study developed from 2019 to 2021 focusing on patients suspected of beta-lactams allergy (n = 688). By means of an allergy test, it was cleared out if they were actually allergic. Later, we checked if the patient was still labelled as allergic in their medical record. Tracking through the digital health services card, we followed up if the antibiotic was ever prescribed again, and if the drug was then dispensed to the patient.Results: 11.3% of the patients showed hypersensitivity to beta-lactams. Nonetheless, 33.1% of the patients were still considered allergic to these antibiotics in their medical record even though not being such. 32% of the patients --who had their allergy confirmed --had been labelled without the general practitioner's acknowledgment, and 32.8% had even been prescribed a beta-lactam again.Conclusions: Discarding any allergy to beta-lactams is as important as registering the allergy on medical records after testing the patient. A remarkable quantity of non-allergic patients is still addressed as actual allergic, in spite not being such. Labelling patients as B-lactams allergic may have consequences, short-term and long-term, for the patient but also for the health service budget.(c) 2022 Sociedad Espanola de Medicos de Atencion Primaria (SEMERGEN). Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Hypersensitivity reactions to beta-lactams in children
    Graham, Francois
    Tsabouri, Sophia
    Caubet, Jean-Christoph
    CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 18 (04) : 284 - 290
  • [2] Patterns of response and drugs involved in hypersensitivity reactions to beta-lactams in children
    Torres-Rojas, Isabel
    Perez-Alzate, Diana
    Luisa Somoza, Maria
    Haroun Diaz, Elisa
    Ruano Perez, Francisco Javier
    Prieto-Moreno Pfeifer, Ana
    Jimenez-Rodriguez, Teodorikez W.
    Fernandez Sanchez, Javier
    Blanca Gomez, Miguel
    Canto Diez, Gabriela
    Blanca-Lopez, Natalia
    PEDIATRIC ALLERGY AND IMMUNOLOGY, 2021, 32 (08) : 1788 - 1795
  • [3] Diagnosis and selection of alternative antibiotics in beta-lactams hypersensitivity reactions: Current recommendations and challenges
    Kanannejad, Zahra
    Pourvali, Ali
    Esmaeilzadeh, Hossein
    Shoormasti, Raheleh Shokouhi
    Fazlollahi, Mohammad Reza
    Fallahpour, Morteza
    Zaremehrjardi, Fatemeh
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 122
  • [4] Analysis of the Costs Associated With the Elective Evaluation of Patients Labelled as Allergic to Beta-Lactams or Nonsteroidal Antiinflamatory Agents
    Sobrino-Garcia, Miriam
    Moreno, Esther M.
    Munoz-Bellido, Francisco J.
    Gracia-Bara, Maria T.
    Laffond, Elena
    Dona, Inmaculada
    Martin, Cristina
    Macias, Eva M.
    de Arriba, Sonia
    Campanon, Valle
    Gallardo, Alicia
    Davila, Ignacio
    FRONTIERS IN PHARMACOLOGY, 2020, 11
  • [5] Are skin tests useful after benign immediate reactions to beta-lactams in children?
    Mahjoub, Bouchra
    Marsac, Charlotte
    Ponvert, Claude
    Delacourt, Christophe
    Faour, Hassan
    Garcelon, Nicolas
    Lezmi, Guillaume
    CLINICAL AND EXPERIMENTAL ALLERGY, 2024, 54 (06) : 441 - 443
  • [6] ALLERGIC REACTIONS TO BETA-LACTAMS - STUDIES IN A GROUP OF PATIENTS ALLERGIC TO PENICILLIN AND EVALUATION OF CROSS-REACTIVITY WITH CEPHALOSPORIN
    AUDICANA, M
    BERNAOLA, G
    URRUTIA, I
    ECHECHIPIA, S
    GASTAMINZA, G
    MUNOZ, D
    FERNANDEZ, E
    DECORRES, LF
    ALLERGY, 1994, 49 (02) : 108 - 113
  • [7] The Importance of Amoxicillin and Amoxicillin-Clavulanate Determinants in the Diagnosis of Immediate Allergic Reactions to β-Lactams
    Confino-Cohen, Ronit
    Rosman, Yossi
    Lachover, Idit
    Shafrir, Keren Meir
    Goldberg, Arnon
    INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2016, 170 (01) : 62 - 66
  • [8] Management of allergy to penicillins and other beta-lactams
    Mirakian, R.
    Leech, S. C.
    Krishna, M. T.
    Richter, A. G.
    Huber, P. A. J.
    Farooque, S.
    Khan, N.
    Pirmohamed, M.
    Clark, A. T.
    Nasser, S. M.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2015, 45 (02) : 300 - 327
  • [9] Diagnostic algorithms and alternative beta-lactams in delayed hypersensitivity to beta-lactams
    Delcroix, F.
    Nicolas, J. -F.
    REVUE FRANCAISE D ALLERGOLOGIE, 2018, 58 (06): : 447 - 449
  • [10] Allergy to antibacterials: The problem with beta-lactams and sulfonamides
    Cerny, A
    Pichler, W
    PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 1998, 7 : S23 - S36