Function and regulation of TMC1, LHFPL5, and TMIE in auditory mechanotransduction complex

被引:0
|
作者
Yu, Xiaojie [1 ]
Li, Yulin [1 ]
Feng, Wanying [1 ]
Huang, Pingbo [1 ]
机构
[1] Hong Kong Univ Sci & Technol, Div Life Sci, Kowloon, Hong Kong, Peoples R China
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
2144-Symp
引用
收藏
页码:441A / 441A
页数:1
相关论文
共 50 条
  • [21] LOXHD1 is indispensable for maintaining TMC1 auditory mechanosensitive channels at the site of force transmission
    Pei Wang
    Katharine K. Miller
    Enqi He
    Siddhant S. Dhawan
    Christopher L. Cunningham
    Nicolas Grillet
    Nature Communications, 15 (1)
  • [22] Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function
    Nakanishi, Hiroshi
    Kurima, Kiyoto
    Pan, Bifeng
    Wangemann, Philine
    Fitzgerald, Tracy S.
    Geleoc, Gwenaelle S.
    Holt, Jeffrey R.
    Griffith, Andrew J.
    SCIENTIFIC REPORTS, 2018, 8
  • [23] Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function
    Hiroshi Nakanishi
    Kiyoto Kurima
    Bifeng Pan
    Philine Wangemann
    Tracy S. Fitzgerald
    Gwenaëlle S. Géléoc
    Jeffrey R. Holt
    Andrew J. Griffith
    Scientific Reports, 8
  • [24] Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins
    Ballesteros, Angela
    Fenollar-Ferrer, Cristina
    Swartz, Kenton Jon
    ELIFE, 2018, 7
  • [25] Regulation of membrane homeostasis by TMC1 mechanoelectrical transduction channels is essential for hearing
    Morcillo, Angela Ballesteros
    BIOPHYSICAL JOURNAL, 2022, 121 (03) : 437A - 437A
  • [26] Structural Relationship between the Putative Hair Cell Mechanotransduction Channel TMC1 and TMEM16 Proteins
    Morcillo, Angela Ballesteros
    Fenollar-Ferrer, Maria Cristina
    Swartz, Kenton J.
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 460A - 460A
  • [27] Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices
    Akyuz, Nurunisa
    Karavitaki, K. Domenica
    Pan, Bifeng
    Tamvakologos, Panos, I
    Brock, Kelly P.
    Li, Yaqiao
    Marks, Debora S.
    Corey, David P.
    SCIENCE ADVANCES, 2022, 8 (28):
  • [28] Subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize in zebrafish sensory hair cells
    Pacentine, Itallia V.
    Nicolson, Teresa
    PLOS GENETICS, 2019, 15 (02):
  • [29] TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice
    Liu, Shuang
    Wang, Shufeng
    Zou, Linzhi
    Li, Jie
    Song, Chenmeng
    Chen, Jiaofeng
    Hu, Qun
    Liu, Lian
    Huang, Pingbo
    Xiong, Wei
    ELIFE, 2019, 8
  • [30] The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells
    Beurg, Maryline
    Goldring, Adam C.
    Fettiplace, Robert
    JOURNAL OF GENERAL PHYSIOLOGY, 2015, 146 (03): : 233 - 243