Methamphetamine: Mechanism of Action and Chinese Herbal Medicine Treatment for Its Addiction

被引:6
作者
Zeng, Rui [1 ]
Pu, Hong-yu [2 ]
Zhang, Xin-yue [1 ]
Yao, Meng-lin [1 ]
Sun, Qin [1 ]
机构
[1] Southwest Med Univ, Affiliated Tradit Chinese Med Hosp, Luzhou 646000, Sichuan, Peoples R China
[2] North Sichuan Med Coll, Nanchong 637000, Sichuan, Peoples R China
关键词
methamphetamine; mechanism; addiction; neurotoxicity; Chinese herbal medicine; treatment; MITOCHONDRIAL DYSFUNCTION; LEVO-TETRAHYDROPALMATINE; NEUROTROPHIC FACTOR; PANAX-GINSENG; BRAIN; NEUROTOXICITY; HIPPOCAMPAL; ACTIVATION; APOPTOSIS; MEMORY;
D O I
10.1007/s11655-023-3635-y
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
With the proliferation of synthetic drugs, research on the mechanism of action of addictive drugs and treatment methods is of great significance. Among them, methamphetamine (METH) is the most representative amphetamine synthetic drug, and the treatment of METH addiction has become an urgent medical and social problem. In recent years, the therapeutic effects of Chinese herbal medicines on METH addiction have gained widespread attention because of their non-addictiveness, multiple targets, low side effects, low cost, and other characteristics. Previous studies have identified a variety of Chinese herbal medicines with effects on METH addiction. Based on the research on METH in recent years, this article summarizes the mechanism of action of METH as the starting point and briefly reviews the Chinese herbal medicine-based treatment of METH.
引用
收藏
页码:665 / 672
页数:8
相关论文
共 81 条
  • [11] Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway
    Coelho-Santos, Vanessa
    Goncalves, Joana
    Fontes-Ribeiro, Carlos
    Silva, Ana Paula
    [J]. JOURNAL OF NEUROINFLAMMATION, 2012, 9
  • [12] Methamphetamine: An update on epidemiology, pharmacology, clinical phenomenology, and treatment literature
    Courtney, Kelly E.
    Ray, Lara A.
    [J]. DRUG AND ALCOHOL DEPENDENCE, 2014, 143 : 11 - 21
  • [13] A review of the clinical pharmacology of methamphetamine
    Cruickshank, Christopher C.
    Dyer, Kyle R.
    [J]. ADDICTION, 2009, 104 (07) : 1085 - 1099
  • [14] METHAMPHETAMINE NEUROTOXICITY INVOLVES VACUOLATION OF ENDOCYTIC ORGANELLES AND DOPAMINE-DEPENDENT INTRACELLULAR OXIDATIVE STRESS
    CUBELLS, JF
    RAYPORT, S
    RAJENDRAN, G
    SULZER, D
    [J]. JOURNAL OF NEUROSCIENCE, 1994, 14 (04) : 2260 - 2271
  • [15] Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine
    Cunha-Oliveira, Teresa
    Rego, A. Cristina
    Cardoso, Sandra M.
    Borges, Fernanda
    Swerdlow, Russell H.
    Macedo, Tice
    de Oliveira, Catarina R.
    [J]. BRAIN RESEARCH, 2006, 1089 : 44 - 54
  • [16] Methamphetamine induces apoptosis in an immortalized rat striatal cell line by activating the mitochondrial cell death pathway
    Deng, XL
    Cai, NS
    McCoy, MT
    Chen, WG
    Trush, MA
    Cadet, JL
    [J]. NEUROPHARMACOLOGY, 2002, 42 (06) : 837 - 845
  • [17] Hippocampal volume reduction in female but not male recent abstinent methamphetamine users
    Du, Jiang
    Quan, Meina
    Zhuang, Wenxu
    Zhong, Na
    Jiang, Haifeng
    Kennedy, David N.
    Harrington, Amy
    Ziedonis, Douglas
    Fan, Xiaoduo
    Zhao, Min
    [J]. BEHAVIOURAL BRAIN RESEARCH, 2015, 289 : 78 - 83
  • [18] Neuroprotective effect of ghrelin in methamphetamine-treated male rats
    Fallahi, Solmaz
    Babri, Shirin
    Farajdokht, Fereshteh
    Ghiasi, Rafighe
    Zangbar, Hamid Soltani
    Karimi, Pouran
    Mohaddes, Gisou
    [J]. NEUROSCIENCE LETTERS, 2019, 707
  • [19] Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania
    Fries, Gabriel R.
    Valvassori, Samira S.
    Bock, Hugo
    Stertz, Laura
    da Silva Magalhaes, Pedro Vieira
    Mariot, Edimilson
    Varela, Roger B.
    Kauer-Sant'Anna, Marcia
    Quevedo, Joao
    Kapczinski, Flavio
    Saraiva-Pereira, Maria Luiza
    [J]. JOURNAL OF PSYCHIATRIC RESEARCH, 2015, 68 : 329 - 336
  • [20] Pseudoginsenoside-F11 inhibits methamphetamine-induced behaviors by regulating dopaminergic and GABAergic neurons in the nucleus accumbens
    Fu, Kequan
    Lin, Huiyang
    Miyamoto, Yoshiaki
    Wu, Chunfu
    Yang, Jingyu
    Uno, Kyosuke
    Nitta, Atsumi
    [J]. PSYCHOPHARMACOLOGY, 2016, 233 (05) : 831 - 840