Advances in microneedles research based on promoting hair regrowth

被引：40

作者：

Zhou, Yanjun ^{[1
]}

Jia, Luan ^{[1
]}

Zhou, Di ^{[1
]}

Chen, Gang ^{[1
]}

Fu, Qiang ^{[2
]}

Li, Ning ^{[1
,3
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Key Lab TCM Mat Basis Study & Innovat Drug Dev She, Shenyang 110016, Peoples R China

[2] Shenyang Pharmaceut Univ, Wuya Coll Innovat, 103 Wenhua Rd, Shenyang 110016, Peoples R China

[3] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Wenhua Rd 103, Shenyang 110016, Peoples R China

来源：

JOURNAL OF CONTROLLED RELEASE | 2023年 / 353卷

基金：

中国国家自然科学基金;

关键词：

Alopecia; Hair regrowth; Microneedles; Transdermal drug delivery; ANDROGENETIC ALOPECIA; DRUG-DELIVERY; CICATRICIAL ALOPECIA; TRANSDERMAL DELIVERY; GROWTH; MANAGEMENT; MINOXIDIL; CEDROL; CELLS; FINASTERIDE;

D O I：

10.1016/j.jconrel.2022.12.040

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alopecia is the most common and difficult-to-treat hair disorder. It usually brings a significant psychological burden to the patients. With the growing popularity of alopecia, the study of alopecia has gained more attention. Currently, only minoxidil and finasteride have been approved by the FDA for the treatment of alopecia, but the efficacy has always been unsatisfactory. As a new form of transdermal drug delivery, microneedles have been widely used in the treatment of alopecia and have proven to be effective. Microneedles delivery can improve the efficiency of local drug delivery and patients' compliance, which can achieve better therapeutic effects on hair -related diseases. Therefore, microneedles have gained much attention in the field of alopecia and hair regrowth promotion in recent years. This review summarizes the last decade of research on the microneedles delivery design for the treatment of alopecia or promotion of hair regrowth and provides a comprehensive evaluation of this field.

引用

页码：965 / 974

页数：10