The Hepatitis B Virus Genotypes E to J: The Overlooked Genotypes

被引:5
作者
Toye, Rayana Maryse [1 ]
Loureiro, Carmen Luisa [2 ]
Jaspe, Rossana Celeste [2 ]
Zoulim, Fabien [1 ]
Pujol, Flor Helene [2 ,3 ]
Chemin, Isabelle [1 ]
机构
[1] Inserm, Ctr Rech Cancerol Lyon CRCL, U1052, 151 Cours Albert Thomas, F-69003 Lyon, France
[2] Inst Venezolano Invest Cient IVIC, Ctr Microbiol & Biol Celular CMBC, Lab Virol Mol, Caracas 1020A, Venezuela
[3] Univ Lyon 2, Inst Etud Avancees, Coll Lyon, F-69007 Lyon, France
关键词
hepatitis B virus; genotype E; genotype F; genotype G; genotype H; genotype I; genotype J; Africa; Latin America; Asia; GENETIC DIVERSITY; RECOMBINANT GENOTYPE; EVOLUTIONARY HISTORY; HBV GENOTYPES; INFECTION; STRAINS; GENOME; SUBGENOTYPES; TRANSMISSION; MUTATIONS;
D O I
10.3390/microorganisms11081908
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Hepatitis B virus (HBV) genotypes E to J are understudied genotypes. Genotype E is found almost exclusively in West Africa. Genotypes F and H are found in America and are rare in other parts of the world. The distribution of genotype G is not completely known. Genotypes I and J are found in Asia and probably result from recombination events with other genotypes. The number of reported sequences for HBV genotypes E to J is small compared to other genotypes, which could impact phylogenetic and pairwise distance analyses. Genotype F is the most divergent of the HBV genotypes and is subdivided into six subgenotypes F1 to F6. Genotype E may be a recent genotype circulating almost exclusively in sub-Saharan Africa. Genotype J is a putative genotype originating from a single Japanese patient. The paucity of data from sub-Saharan Africa and Latin America is due to the under-representation of these regions in clinical and research cohorts. The purpose of this review is to highlight the need for further research on HBV genotypes E to J, which appear to be overlooked genotypes.
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页数:17
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