The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges

被引：2
作者：
Jung, Jungchan [1 ]
Han, Hyunho [1 ]
机构：
[1] Yonsei Univ, Coll Med, Urol Sci Inst, Dept Urol, Seoul 03722, South Korea
来源：
HELIYON | 2024年 / 10卷 / 02期
基金：
新加坡国家研究基金会;
关键词：
Relaxin; Insulin -like peptide; Cancer; TME; ECM; INSULIN-LIKE PEPTIDE; BREAST-CANCER CELLS; H2; RELAXIN; GROWTH-FACTOR; RECEPTOR RXFP1; SERUM RELAXIN; EXPRESSION; GENE; ACTIVATION; DIFFERENTIATION;
D O I：
10.1016/j.heliyon.2024.e24463
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Relaxin-like peptide family exhibit differential expression patterns in various types of cancers and play a role in cancer development. This family participates in tumorigenic processes encompassing proliferation, migration, invasion, tumor microenvironment, immune microenvironment, and anti-cancer resistance, ultimately influencing patient prognosis. In this review, we explore the mechanisms underlying the interaction between the RLN-like peptide family and tumors and provide an overview of therapeutic approaches utilizing this interaction.
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页数：17
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