Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors

被引：1

作者：

Behrendt, Paulina ^{[1
]}

Boettcher, Michael ^{[1
,2
]}

Zierke, Kira Tabea ^{[1
]}

Najem, Safiullah ^{[1
]}

Zapf, Holger ^{[3
]}

Reinshagen, Konrad ^{[1
]}

Woessmann, Wilhelm ^{[3
]}

Boettcher, Johannes ^{[4
]}

机构：

[1] Univ Med Ctr Hamburg Eppendorf, Dept Pediat Surg, Martinistr 52, D-20246 Hamburg, Germany

[2] Heidelberg Univ, Univ Med Ctr Mannheim, Dept Pediat Surg, Theodor Kutzer Ufer 1-3, D-68167 Mannheim, Germany

[3] Univ Med Ctr Hamburg Eppendorf, Dept Pediat Hematol & Oncol, Martinistr 52, D-20246 Hamburg, Germany

[4] Univ Med Ctr Hamburg Eppendorf, Dept Child & Adolescent Psychiat Psychosomat & Psy, Martinistr 52, D-20246 Hamburg, Germany

来源：

CHILDREN-BASEL | 2023年 / 10卷 / 10期

关键词：

embryonal abdominal tumors; health-related quality of life; mental health; rare diseases; pediatric surgery; GENERIC CORE SCALES; RECEIVING TREATMENT; RISK; RELIABILITY; EXPERIENCE; SYMPTOMS; VALIDITY; VERSION;

D O I：

10.3390/children10101720

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

(1) Background: Embryonal abdominal tumors are one of the most common entities of solid childhood cancer. The present study investigates the Health-Related Quality of Life (HRQoL) and the mental health of children to obtain a comprehensive picture of their health status and uncover a possible gap in healthcare. (2) Methods: The sample consisted of 54 children who were treated for embryonal abdominal tumors and a control group of 46 children who received uncomplicated outpatient surgery. The HRQoL and the mental health were assessed by the parent proxy reports of the questionnaires Pediatric Quality of Life Inventory (PedsQL) and Strengths and Difficulties Questionnaire (SDQ). (3) Results: Children with embryonal abdominal tumors showed significantly lower HRQoL and mental health values compared to the norm data. The index group showed lower values in the social subscales of HRQoL and mental health compared to the control group. (4) Conclusions: Embryonal abdominal tumors affect the well-being of children. There is still a gap in healthcare due to children's HRQoL and mental health, especially regarding social development. It is essential to further advance the psychological care of children and improve their chances to develop social relationships.

引用

页数：11

共 39 条

[1] Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas: 10 year single-center experience and literature review [J].

Ayllon Teran, Dolores ;

Gomez Beltran, Oscar ;

Ciria Bru, Ruben ;

Mateos Gonzalez, Elena ;

Pena Rosa, Maria Jose ;

Luque Molina, Antonio ;

Lopez Cillero, Pedro ;

Briceno Delgado, Javier .

WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (29) :10137-10143

[2] Mental Health of Siblings of Children with Rare Congenital Surgical Diseases during the COVID-19 Pandemic [J].

Boettcher, Johannes ;

Nazarian, Rojin ;

Fuerboeter, Mareike ;

Liedtke, Anna ;

Wiegand-Grefe, Silke ;

Reinshagen, Konrad ;

Boettcher, Michael .

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, 2022, 32 (05) :422-428

[3] Depression in pediatric chronic illness -: A diathesis-stress model [J].

Burke, P ;

Elliott, M .

PSYCHOSOMATICS, 1999, 40 (01) :5-17

[4] The PedsQL™ -: Reliability and validity of the short-form generic core scales and asthma module [J].

Chan, KS ;

Mangione-Smith, R ;

Burwinkle, TM ;

Rosen, M ;

Varni, JW .

MEDICAL CARE, 2005, 43 (03) :256-265

[5] Neuroblastoma [J].

Chung, Christine ;

Boterberg, Tom ;

Lucas, John ;

Panoff, Joseph ;

Valteau-Couanet, Dominique ;

Hero, Barbara ;

Bagatell, Rochelle ;

Hill-Kayser, Christine E. .

PEDIATRIC BLOOD & CANCER, 2021, 68

[6] Quality of Life in Rare Genetic Conditions: A Systematic Review of the Literature [J].

Cohen, Julie S. ;

Biesecker, Barbara B. .

AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2010, 152A (05) :1136-1156

[7] GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma [J].

Del Bufalo, Francesca ;

De Angelis, Biagio ;

Caruana, Ignazio ;

Del Baldo, Giada ;

De Ioris, Maria A. ;

Serra, Annalisa ;

Mastronuzzi, Angela ;

Cefalo, Maria G. ;

Pagliara, Daria ;

Amicucci, Matteo ;

Li Pira, Giuseppina ;

Leone, Giovanna ;

Bertaina, Valentina ;

Sinibaldi, Matilde ;

Di Cecca, Stefano ;

Guercio, Marika ;

Abbaszadeh, Zeinab ;

Iaffaldano, Laura ;

Gunetti, Monica ;

Iacovelli, Stefano ;

Bugianesi, Rossana ;

Macchia, Stefania ;

Algeri, Mattia ;

Merli, Pietro ;

Galaverna, Federica ;

Abbas, Rachid ;

Garganese, Maria C. ;

Villani, Maria F. ;

Colafati, Giovanna S. ;

Bonetti, Federico ;

Rabusin, Marco ;

Perruccio, Katia ;

Folsi, Veronica ;

Quintarelli, Concetta ;

Locatelli, Franco .

NEW ENGLAND JOURNAL OF MEDICINE, 2023, 388 (14) :1284-1295

[8] Health-related quality of life among children, young people and adults with esophageal atresia: a review of the literature and recommendations for future research [J].

Dellenmark-Blom, Michaela ;

Chaplin, John Eric ;

Gatzinsky, Vladimir ;

Jonsson, Linus ;

Abrahamson, Kate .

QUALITY OF LIFE RESEARCH, 2015, 24 (10) :2433-2445

[9] Review of 11 national policies for rare diseases in the context of key patient needs [J].

Dharssi, Safiyya ;

Wong-Rieger, Durhane ;

Harold, Matthew ;

Terry, Sharon .

ORPHANET JOURNAL OF RARE DISEASES, 2017, 12

[10] Insights into the Chemical Biology of Childhood Embryonal Solid Tumors by NMR-Based Metabolomics [J].

Escobar, Melissa Quintero ;

Maschietto, Mariana ;

Krepischi, Ana C., V ;

Avramovic, Natasa ;

Tasic, Ljubica .

BIOMOLECULES, 2019, 9 (12)

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