Reproductive performance of lactating dairy cows with elevated milk β-hydroxybutyrate levels during first 6 weeks of lactation

被引:4
作者
Alemu, Teshome Wondie [1 ]
Santschi, Debora E. [2 ]
Cue, Roger I. [1 ]
Duggavathi, Raj [1 ]
机构
[1] McGill Univ, Dept Anim Sci, Ste Anne De Bellevue, PQ H9X 3V9, Canada
[2] Lactanet, Ste Anne De Bellevue, PQ H9X 3R4, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
early lactation; elevated milk BHB; Holstein cow; reproductive performance; BETA-HYDROXYBUTYRATE CONCENTRATIONS; NONESTERIFIED FATTY-ACIDS; NEGATIVE-ENERGY BALANCE; BODY CONDITION SCORE; SUBCLINICAL KETOSIS; CLINICAL KETOSIS; KETONE-BODIES; RISK-FACTORS; YIELD; HYPERKETONEMIA;
D O I
10.3168/jds.2022-22406
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Although there is evidence that ketosis negatively affects fertility, the effect of late and early ketosis on the reproductive performance of lactating cows has not been systematically investigated. The aim of this study was to evaluate the association between time and amplitude of elevated milk BHB (EMB) occurring within 42 d in milk (DIM) and subsequent reproduc-tive performance of lactating Holstein cows. The dairy herd information data of 30,413 cows with 2 test-day milk BHB recordings during early lactation periods 1 and 2 (5-14 and 15-42 DIM, respectively) assessed as negative (<0.15 mmol/L), suspect (0.15-0.19 mmol/L), or positive (& GE;0.2 mmol/L) for EMB were used in this study. Based on the time and amplitude of milk BHB, cows were grouped into 7 groups: (1) healthy cows negative in both periods 1 and 2 were classified as NEG; (2) suspect in period 1 and negative in period 2: EARLY_SUSP; (3) suspect in period 1 and suspect/ positive in period 2: EARLY_SUSP_Pro; (4) positive in period 1 and negative in period 2: EARLY_POS; (5) positive in period 1 and suspect/positive in period 2: EARLY_POS_Pro; (6) negative in period 1 and suspect in period 2: LATE_SUSP; and (7) negative in period 1 and positive in period 2: LATE_POS. The overall prevalence of EMB within 42 DIM was 27.4%, with the highest prevalence being EARLY_SUSP (10.49%). Cows in EARLY_POS and EARLY_POS_Pro, but not other EMB categories, had a longer interval from calv-ing to first service compared with NEG cows. For the reproductive parameters, first service to conception in-terval, days open and calving interval, cows in all EMB groups except EARLY_SUSP had longer intervals com-pared with NEG cows. These data indicate that there is a negative association between EMB within 42 d and reproductive performance after the voluntary waiting period. The intriguing findings of this study are the unaltered reproductive performance of EARLY_SUSP cows, and the negative association between late EMB and reproductive performance. Hence, monitoring and prevention of ketosis during the first 6 wk of lactation is necessary to optimize reproductive performance of lactating dairy cows.
引用
收藏
页码:5165 / 5181
页数:17
相关论文
共 40 条
[1]  
Alemu Teshome, 2023, Figshare, DOI 10.6084/m9.figshare.22718047.v1
[2]   Invited review: β-hydroxybutyrate concentration in blood and milk and its associations with cow performance [J].
Benedet, A. ;
Manuelian, C. L. ;
Zidi, A. ;
Penasa, M. ;
De Marchi, M. .
ANIMAL, 2019, 13 (08) :1676-1689
[3]   A field study to determine the prevalence, dairy herd management systems, and fresh cow clinical conditions associated with ketosis in western European dairy herds [J].
Berge, Anna C. ;
Vertenten, Geert .
JOURNAL OF DAIRY SCIENCE, 2014, 97 (04) :2145-2154
[4]   GENETIC-ASPECTS OF MILK-YIELD AND REPRODUCTIVE-PERFORMANCE [J].
BERGER, PJ ;
SHANKS, RD ;
FREEMAN, AE ;
LABEN, RC .
JOURNAL OF DAIRY SCIENCE, 1981, 64 (01) :114-122
[5]   Evaluation of the use of nonesterified fatty acids and β-hydroxybutyrate concentrations in pooled serum samples for herd-based detection of subclinical ketosis in dairy cows during the first week after parturition [J].
Borchardt, Stefan ;
Staufenbiel, Rudolf .
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2012, 240 (08) :1003-1011
[6]   The association of serum metabolites in the transition period with milk production and early-lactation reproductive performance [J].
Chapinal, N. ;
Carson, M. E. ;
LeBlanc, S. J. ;
Leslie, K. E. ;
Godden, S. ;
Capel, M. ;
Santos, J. E. P. ;
Overton, M. W. ;
Duffield, T. F. .
JOURNAL OF DAIRY SCIENCE, 2012, 95 (03) :1301-1309
[7]  
COX DR, 1972, J R STAT SOC B, V34, P187
[8]   Accuracy of milk ketone bodies from flow-injection analysis for the diagnosis of hyperketonemia in dairy cows [J].
Denis-Robichaud, J. ;
Dubuc, J. ;
Lefebvre, D. ;
DesCoteaux, L. .
JOURNAL OF DAIRY SCIENCE, 2014, 97 (06) :3364-3370
[9]   Impact of hyperketonemia in early lactation dairy cows on health and production [J].
Duffield, T. F. ;
Lissemore, K. D. ;
McBride, B. W. ;
Leslie, K. E. .
JOURNAL OF DAIRY SCIENCE, 2009, 92 (02) :571-580
[10]   Efficacy of monensin for the prevention of subclinical ketosis in lactating dairy cows [J].
Duffield, TF ;
Sandals, D ;
Leslie, KE ;
Lissemore, K ;
McBride, BW ;
Lumsden, JH ;
Dick, P ;
Bagg, R .
JOURNAL OF DAIRY SCIENCE, 1998, 81 (11) :2866-2873