Regio- and Stereoselective Iodoamination of Ferrocene-Containing Allenylphosphonates: Synthesis of Multifunctional Tetrasubstituted Allylic Amines and Allylic Azides

被引：2

作者：

Guo, Le ^{[1
,2
]}

Zhao, Wanrong ^{[1
]}

Gao, Yanpeng ^{[2
]}

Wu, Meimei ^{[2
]}

Chen, Shufeng ^{[1
]}

机构：

[1] Inner Mongolia Univ, Dept Chem & Chem Engn, Hohhot 010021, Peoples R China

[2] Ordos Inst Technol, Coll Chem Engn, Ordos 017000, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 03期

基金：

中国国家自然科学基金;

关键词：

BIOORGANOMETALLIC CHEMISTRY; STRUCTURAL DIVERSITY; PALLADIUM; ALLENES; HYDROAMINATION; FERROCENYLALLENE; HETEROCYCLES; COMPLEXES; CATALYSIS; AZIDATION;

D O I：

10.1021/acs.joc.3c02686

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and practical methodology for the regio- and stereoselective synthesis of multifunctional tetrasubstituted allylic amines and azides based on iodoamination of ferrocene-containing allenylphosphonates with anilines and sodium azide is described. A tetrasubstituted olefin moiety, as well as an iodine atom, a phosphonate, and a ferrocene group, are installed to the allylic amine motif simultaneously in moderate to good yields.

引用

页码：1956 / 1966

页数：11

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