Colorectal Cancer: Current Updates and Future Perspectives

被引：50

作者：

Marcellinaro, Rosa ^{[1
]}

Spoletini, Domenico ^{[1
]}

Grieco, Michele ^{[1
]}

Avella, Pasquale ^{[2
,3
]}

Cappuccio, Micaela ^{[2
]}

Troiano, Raffaele ^{[1
]}

Lisi, Giorgio ^{[1
]}

Garbarino, Giovanni M. ^{[1
]}

Carlini, Massimo ^{[1
]}

机构：

[1] S Eugenio Hosp, Dept Gen Surg, I-00144 Rome, Italy

[2] Univ Naples Federico II, Dept Clin Med & Surg, I-80138 Naples, Italy

[3] Pineta Grande Hosp, Hepatobiliary & Pancreat Surg Unit, I-81030 Caserta, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 01期

关键词：

colorectal cancer; incidence; mortality; screening; survival; LIVER METASTASES; PREOPERATIVE CHEMOTHERAPY; MAJOR HEPATECTOMY; LONG-TERM; RESECTION; SURGERY; RISK; SURVIVAL; EPIDEMIOLOGY; POLYPECTOMY;

D O I：

10.3390/jcm13010040

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Colorectal cancer is a frequent neoplasm in western countries, mainly due to dietary and behavioral factors. Its incidence is growing in developing countries for the westernization of foods and lifestyles. An increased incidence rate is observed in patients under 45 years of age. In recent years, the mortality for CRC is decreased, but this trend is slowing. The mortality rate is reducing in those countries where prevention and treatments have been implemented. The survival is increased to over 65%. This trend reflects earlier detection of CRC through routine clinical examinations and screening, more accurate staging through advances in imaging, improvements in surgical techniques, and advances in chemotherapy and radiation. The most important predictor of survival is the stage at diagnosis. The screening programs are able to reduce incidence and mortality rates of CRC. The aim of this paper is to provide a comprehensive overview of incidence, mortality, and survival rate for CRC.

引用

页数：12

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