Case study on the treatment of dopamine dysregulation syndrome

BACKGROUND: The clinical manifestations of Parkinson's disease (PD) are bradykinesia and abnormal walking postures. Patients with PD are prone to complications such as drug addiction, which may not only lead to cognitive, behavioral, and affective disorders but also have irreversible impacts on patients' body indexes. CASE DESCRIPTION: In this study, the treatment regimen for a patient with dopamine dysregulation syndrome was adjusted to allow for the withdrawal of Trastal, gradual decrease of Madopar, and the addition of Comtan and clozapine. While the body indexes effectively improved, the patient did not experience negative side effects. CONCLUSION: Reducing the dosage of Madopar and reasonably applying the treatment regimen can improve the clinical treatment effect and improve the quality of life of patients.