Predominance of High-Level Tetracycline-Resistant Neisseria gonorrhoeae in Kenya: Implications for Global Implementation of Doxycycline Postexposure Prophylaxis for Prevention of Sexually Transmitted Infections

被引：11

作者：

Soge, Olusegun. O. ^{[1
,2
,3
,9
]}

Issema, Rodal ^{[4
]}

Bukusi, Elizabeth M. ^{[1
,5
]}

Baeten, Jared. M. ^{[1
,6
]}

Mujugira, Andrew

Celum, Connie ^{[1
,2
]}

McClelland, R. Scott ^{[1
,2
]}

Stewart, Jenell ^{[7
,8
]}

机构：

[1] Univ Washington, Dept Global Hlth, Seattle, WA USA

[2] Univ Washington, Dept Med, Seattle, WA USA

[3] Univ Washington, Dept Lab Med & Pathol, Seattle, WA USA

[4] Univ Washington, Dept Epidemiol, Seattle, WA USA

[5] Univ Washington, Dept Obstet & Gynecol, Seattle, WA USA

[6] Kenya Med Res Inst KEMRI, Nairobi, Kenya

[7] Univ Minnesota, Hennepin Healthcare Res Inst, Minneapolis, MN USA

[8] Univ Minnesota, Dept Med, Minneapolis, MN USA

[9] Univ Washington, Harborview Med Ctr, 325 9th Ave Box 359931, Seattle, WA 98104 USA

来源：

SEXUALLY TRANSMITTED DISEASES | 2023年 / 50卷 / 05期

基金：

美国国家卫生研究院;

关键词：

PREEXPOSURE PROPHYLAXIS; SOUTH-AFRICA; EMERGENCE; WOMEN; MEN; SEX;

D O I：

10.1097/OLQ.0000000000001769

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Using archived Neisseria gonorrhoeae samples from 2008 to 2012, the prevalence of tet(M) genemediating high-level tetracycline resistance in N. gonorrhoeae was 96% among 50 Kenyan women. Determining the local and national prevalence of gonococcal tetracycline resistance and surveillance of gonococcal antimicrobial resistance can inform the implementation of doxycycline postexposure prophylaxis for STI prevention.

引用

页码：317 / 319

页数：3

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