Synthesis of New Cyclohexenone Derivatives Using Potassium Phthalimide as a Green Organocatalyst. One-Pot Microwave-Assisted Synthesis and Antimicrobial Evaluation

被引：2

作者：

Odiya, S. P. ^{[1
]}

Das, S. P. ^{[1
,2
]}

Boruah, J. J. ^{[1
]}

Rajani, D. P. ^{[3
,4
]}

机构：

[1] RK Univ, Sch Sci, Dept Chem, Rajkot 360020, Gujarat, India

[2] Chandigarh Univ, Univ Inst Sci, Dept Chem, Mohali 140413, Punjab, India

[3] Microcare Lab, Surat 395003, Gujarat, India

[4] TB Res Ctr, Surat 395003, Gujarat, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 59卷 / 01期

关键词：

cyclohexenone derivatives; potassium phthalimide (PPI); one-pot synthesis; microwave irradiation; antimicrobial activity; EFFICIENT SYNTHESIS; STARCH SOLUTION; BASE CATALYST; CYCLIC ENONES; NANOPARTICLES; CHEMISTRY; SILICA;

D O I：

10.1134/S107042802301013X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A direct one-pot three-component reaction of 4-acetyl-N-benzylbenzamide, ethyl acetoacetate or methyl acetoacetate, and aromatic aldehydes under microwave irradiation afforded a series of new cyclo-hexenone derivatives. The proposed procedure has the advantages of one-pot reaction, high efficiency, short reaction time, and simple workup. The antimicrobial activity of the obtained cyclohexenone derivatives was tested against a variety of bacteria (E. coli, S. aureus, S. pyogenes, P. aeruginosa) and fungi (C. albicans, A. niger, A. clavatus).

引用

页码：117 / 132

页数：16

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