Strabismus and amblyopia in Africa - a systematic review and meta-analysis

被引:2
作者
Akowuah, Prince Kwaku [1 ,2 ]
Adade, Samuel [1 ]
Nartey, Andrews [1 ]
Owusu, Ebenezer [1 ]
Donkor, Richard [3 ]
Ankamah-Lomotey, Stephen [2 ]
Frimpong, Asafo Agyei [2 ]
Adjei-Anang, Joseph [2 ]
Kobia-Acquah, Emmanuel [2 ,4 ]
机构
[1] Univ Houston, Coll Optometry, 4401 Martin Luther King Blvd, Houston, TX 77004 USA
[2] Kwame Nkrumah Univ Sci & Technol, Dept Optometry & Visual Sci, Kumasi, Ghana
[3] Univ Waterloo, Sch Optometry & Vis Sci, Waterloo, ON, Canada
[4] Technol Univ Dublin, Coll Sci & Hlth, Ctr Eye Res Ireland, Sch Phys Clin & Optometr Sci, Dublin, Ireland
关键词
Africa; amblyopia; meta-analysis; strabismus; systematic review; QUALITY-OF-LIFE; VISUAL IMPAIRMENT; REFRACTIVE ERROR; ANISOMETROPIC AMBLYOPIA; SCHOOL-CHILDREN; EYE DISEASES; HEALTH-CARE; PREVALENCE; SCHOOLCHILDREN; IMPACT;
D O I
10.1080/09273972.2022.2157023
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The objective of this review was to estimate the prevalence of strabismus and amblyopia in Africa. A systematic online literature search was conducted for articles on strabismus and amblyopia in Africa. Meta-analysis was performed, using the Freeman-Tukey double arcsine transformation, to estimate the prevalence of strabismus and amblyopia in Africa. Subgroup analyses were conducted according to age, gender, study year, and type of amblyopia. Meta-regression was used to evaluate the influence of predetermined factors on the prevalence of amblyopia. 8 (1 population-based & 7 school-based) and 21 (3 population-based & 18 school-based) studies on strabismus and amblyopia with sample sizes of 22,355 and 46,841, respectively, were included in the review. Overall prevalence of strabismus in Africa was estimated to be 0.8% (95% CI: 0.4% - 1.4%); exotropia was 0.2% (95% CI: 0.1% - 0.5%) and esotropia was 0.5% (95% CI: 0.1% - 1.2%). Overall prevalence of amblyopia was estimated to be 0.6% (95% CI: 0.3% - 0.9%); refractive and strabismic amblyopia were 1.1% (95% CI: 0.2% - 2.5%) and 0.4% (95% CI: 0.2% - 0.6%), respectively. Prevalence estimate of amblyopia in males was 1.8% (95% CI: 0.7% - 3.3%) and in females was 1.3% (95% CI: 0.4% - 2.6%). There was a significant association between the prevalence of amblyopia and the type of amblyopia (p = .007) and the study year (p = .006). Although there appears to be a relatively low prevalence of strabismus and amblyopia in Africa, there is a dearth of well-designed population-based studies on strabismus and amblyopia in Africa, resulting in the lack of epidemiological information on strabismus and amblyopia within the general African population. Information about the prevalence of strabismus and amblyopia across Africa can inform policy making and design and implementation of public health intervention program.
引用
收藏
页码:31 / 44
页数:14
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