Primary total knee arthroplasty in hemophilic arthropathy

center dot Advanced hemophilic knee arthropathy is a frequent and devastating manifestation of severe hemophilia with significant implications for activities of daily living. center dot Hemophilic arthropathy is caused by repeated bleeding, resulting in joint degeneration, pain, deformity and disability. center dot In patients with hemophilia and advanced disease, total knee arthroplasty (TKA) has proven to be the most successful intervention, improves physical function and reduces knee pain. center dot Hemophilic patients carry additional risks for complications and required specific pre/ postoperative considerations. Expert treatment center should be used to improve patient outcome. center dot Hemophilic patients present significant surgical challenges such as joint destruction, bone loss, severe ankylosis and oligoarticular involvement. The surgeon performing the arthroplasty must be experienced to manage such problems.