Synthesis, Antibacterial, and Antimonooxidase Activity of 4-(2-Methyl-1,3-oxazol-5-yl)benzenesulfonamide

被引：1
作者：
Gasilina, O. A. [1 ,3 ]
Romanycheva, A. A. [1 ]
Shetnev, A. A. [1 ,2 ]
Korsakov, M. K. [1 ,3 ]
机构：
[1] KD Ushinsky Yaroslavl State Pedag Univ, Yaroslavl 150000, Russia
[2] Moscow Inst Phys & Technol, Dolgoprudnyi 141700, Russia
[3] Kosygin State Univ Russia, Moscow 115035, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 11期
基金：
俄罗斯科学基金会;
关键词：
sulfonamides; carbonic anhydrase inhibitors; antibiotic potentiation; anti-MAO effect; CARBONIC-ANHYDRASE IX; BENZENESULFONAMIDES; INHIBITORS; POTENT;
D O I：
10.1134/S1070363223110038
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new method for obtaining 4-(2-methyl-1,3-oxazol-5-yl)benzenesulfonamide, an antiglaucomatous drug candidate oxazopt, was developed using a diazotization reaction. A combined potentiated effect of the antimicrobial action of carbapenems (meropenem) and aminoglycosides (gentamicin) against antibiotic-resistant gram-positive bacteria Enterococcus faecium, Enterococcus faecalis and gram-negative bacteria Escherichia coli, and antimonooxidase effect in vitro was revealed for this compound.
引用
收藏
页码：2749 / 2755
页数：7
相关论文
共 50 条
[21]   An efficient method for the synthesis of novel derivatives 4-{5-[4-(4-amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-phenyl]-3-trifluoromethyl-pyrazol-1-yl}-benzenesulfonamide and their anti-inflammatory potential [J].
Mustafa, Ghulam ;
Angeli, Andrea ;
Zia-ur-Rehman, Muhammad ;
Akbar, Nosheen ;
Ishtiaq, Saiqa ;
Supuran, Claudiu T. .
BIOORGANIC CHEMISTRY, 2019, 91
[22]   Catalytic synthesis and antimicrobial activity of N-(3-chloro-2-oxo-4-phenylazetidin-1-yl)-4-(1H-indol-3-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamides [J].
Desai, Nisheeth C. ;
Bhatt, Malay J. .
HETEROCYCLIC COMMUNICATIONS, 2016, 22 (03) :131-136
[23]   Synthesis and Antibacterial Assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine [J].
Gahtori, P. ;
Das, A. ;
Bhatt, H. .
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 71 (01) :79-82
[24]   Synthesis and Antibacterial Evaluation of (S,Z)-4-methyl-2-(4-oxo-5-((5-substituted phenylfuran-2-yl) methylene)-2-thioxothiazolidin-3-yl) Pentanoic Acids [J].
Song, Ming-Xia ;
Deng, Xian-Qing ;
Wei, Zhi-Yu ;
Zheng, Chang-Ji ;
Wu, Yan ;
An, Chang-Shan ;
Piao, Hu-Ri .
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2015, 14 (01) :89-96
[25]   Synthesis and Macrofilaricidal Activity of Substituted 2-Hydroxy/5-Hydroxy/2-Methyl-1,4-Naphthoquinones [J].
Karunan, Twinkle ;
Mathew, Nisha ;
Srinivasan, Lakshmy ;
Muthuswamy, Kalyanasundaram .
DRUG DEVELOPMENT RESEARCH, 2013, 74 (03) :216-226
[26]   DESIGN, SYNTHESIS, MOLECULAR DOCKING AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF 4- AMINO-N- [(4-OXO-2-(PHENYLAMINO)-4H-CHROMEN-3-YL) METHYLENE]BENZENESULFONAMIDE AND THEIR DERIVATIVES [J].
Chopra, Anuj A. ;
Singh, Lakhwinder ;
Kapoor, V. K. ;
Dhingra, Richa ;
Dhingra, Neelima .
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2019, 10 (06) :3073-3084
[27]   Synthesis, structural, computational, electronic spectra, wave function properties and molecular docking studies of (Z)-4-(((5-methylfuran-2-yl) methylene)amino)-N-(thiazol-2-yl)benzenesulfonamide [J].
Thilagavathi, G. ;
Kanagavalli, A. ;
Jayachitra, R. ;
Padmavathy, M. ;
Elangovan, N. ;
Thomas, Renjith .
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2022, 99 (12)
[28]   Synthesis and Primary Antitumor Screening of 4-[5-(1H-Indol-3-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanamides [J].
Horishny, V. Ya. ;
Matiychuk, V. S. .
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 56 (07) :1146-1152
[29]   Design, synthesis, and antifibrosis evaluation of 4-(benzo-[c][1,2,5]thiadiazol-5-yl)-3(5)-(6-methyl- pyridin-2-yl)pyrazole and 3(5)-(6-methylpyridin-2-yl)-4-(thieno-[3,2,-c]pyridin-2-yl)pyrazole derivatives [J].
Zhu, Wen-Jing ;
Cui, Ben-Wen ;
Wang, Hui Min ;
Nan, Ji-Xing ;
Piao, Hu-Ri ;
Lian, Li-Hua ;
Jin, Cheng Hua .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 180 :15-27
[30]   Synthesis, Crystal Structure and Biological Activity of 2-(3,4-Dichloroisothiazol-5-yl)-4-(trifluoromethyl)-4,5-dihydrothiazol-4-yl-3-methylbenzoate [J].
Zong Guang-Ning ;
Li Feng-Yun ;
Fan Zhi-Jin ;
Mao Wu-Tao ;
Song Hai-Bin ;
Chen Lai ;
Zhu Yu-Jie ;
Xu Jing-Hua ;
Song Yin-Qi ;
Wang Jia-Ran .
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2015, 34 (06) :871-878
12345