Potential mechanisms of action of resveratrol in prevention and therapy for mental disorders

被引：4

作者：

Menegas, Samira ^{[1
]}

Keller, Gabriela S. ^{[1
]}

Possamai-Della, Taise ^{[1
]}

Aguiar-Geraldo, Jorge M. ^{[1
]}

Quevedo, Joao ^{[1
,2
,3
,4
]}

Valvassori, Samira S. ^{[1
,5
]}

机构：

[1] Univ Southern Santa Catarina UNESC, Grad Program Hlth Sci, Translat Psychiat Lab, Criciuma, Brazil

[2] Univ Texas Hlth Sci Ctr Houston UTHealth, McGovern Med Sch, Dept Psychiat & Behav Sci, Translat Psychiat Program, Houston, TX USA

[3] Univ Texas Hlth Sci Ctr Houston UTHealth, Ctr Excellence Mood Disorders, McGovern Med Sch, Dept Psychiat & Behav Sci, Houston, TX USA

[4] Univ Texas Hlth Sci Ctr Houston UTHealth Houston, Ctr Intervent Psychiat, Faillace Dept Psychiat & Behav Sci, Houston, TX USA

[5] Univ Southern Santa Catarina UNESC, Criciuma, SC, Brazil

来源：

JOURNAL OF NUTRITIONAL BIOCHEMISTRY | 2023年 / 121卷

关键词：

Resveratrol; Major depressive disorder; Bipolar disorder; Alzheimer's disease; Autism; DEPRESSIVE-LIKE BEHAVIOR; OXIDATIVE STRESS; DOPAMINE TRANSPORTER; ALZHEIMERS-DISEASE; SIGNALING PATHWAY; RAT MODEL; SCHIZOPHRENIA; INVOLVEMENT; ANXIETY; INFLAMMATION;

D O I：

10.1016/j.jnutbio.2023.109435

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There is a growing body of evidence about the potential of diet and nutrients to improve the population's mental health and the treatment of psychiatric disorders. Some studies have suggested that resveratrol has therapeutic properties in mental disorders, such as major depressive disorder, bipolar disorder, Alzheimer's disease, and autism. In addition, resveratrol is known to induce several benefits modulated by multiple synergistic pathways, which control oxidative stress, inflammation, and cell death. This review collects the currently available data from animal and human studies and discusses the potential mechanisms of action of resveratrol in prevention and therapy for psychiatric disorders.(c) 2023 Elsevier Inc. All rights reserved.

引用

页数：26

共 138 条

[1] Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress [J].

Abd El-Fattah, Amal Ahmed ;

Fahim, Atef Tadros ;

Sadik, Nermin Abdel Hamid ;

Ali, Bassam Mohamed .

BRAIN RESEARCH, 2018, 1701 :227-236

[2] Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior [J].

Abe-Higuchi, Naoko ;

Uchida, Shusaku ;

Yamagata, Hirotaka ;

Higuchi, Fumihiro ;

Hobara, Teruyuki ;

Hara, Kumiko ;

Kobayashi, Ayumi ;

Watanabe, Yoshifumi .

BIOLOGICAL PSYCHIATRY, 2016, 80 (11) :815-826

[3] Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T+ Itpr3tf/J autistic mice [J].

Ahmad, Sheikh F. ;

Ansari, Mushtaq A. ;

Nadeem, Ahmed ;

Bakheet, Saleh A. ;

Alzahrani, Mohammad Z. ;

Alshammari, Musaad A. ;

Alanazi, Wael A. ;

Alasmari, Abdullah F. ;

Attia, Sabry M. .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 829 :70-78

[4] Resveratrol Improves Neuroimmune Dysregulation Through the Inhibition of Neuronal Toll-Like Receptors and COX-2 Signaling in BTBR T+ Itpr3tf/J Mice [J].

Ahmad, Sheikh F. ;

Ansari, Mushtaq A. ;

Nadeem, Ahmed ;

Alzahrani, Mohammad Z. ;

Bakheet, Saleh A. ;

Attia, Sabry M. .

NEUROMOLECULAR MEDICINE, 2018, 20 (01) :133-146

[5] Estrogen, Stress, and Depression: Cognitive and Biological Interactions [J].

Albert, Kimberly M. ;

Newhouse, Paul A. .

ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 15, 2019, 15 :399-423

[6] Evidence for additionally increased apoptosis in the peripheral blood mononuclear cells of major depressive patients with a high risk for suicide [J].

Amidfar, Meysam ;

Kim, Yong-Ku ;

Scaini, Giselli ;

Quevedo, Joao .

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2018, 177 (04) :388-396

[7]

[Anonymous], 2018, WHO ICD-11 for mortality and morbidity statistics, 2018 version

[8]

Ardianto Chrismawan, 2021, Journal of Basic and Clinical Physiology and Pharmacology, V32, P335, DOI 10.1515/jbcpp-2020-0437

[9] The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment [J].

Ashok, A. H. ;

Marques, T. R. ;

Jauhar, S. ;

Nour, M. M. ;

Goodwin, G. M. ;

Young, A. H. ;

Howes, O. D. .

MOLECULAR PSYCHIATRY, 2017, 22 (05) :666-679

[10]

Association A. P., 2013, Diagnostic and Statistical Manual of Mental Disorders, V5th, DOI [10.1590/s2317-17822013000200017, DOI 10.1176/APPI.BOOKS.9780890425596]

← 1 2 3 4 5 6 7 8 9 10 →